ArticleJournal of bacteriology2010
Genomic identification of a novel mutation in hfq that provides multiple benefits in evolving glucose-limited populations of Escherichia coli.
Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment.BMC biology · 2021Article
- Characterization of acetic acid-detoxifying Escherichia coli evolved under phosphate starvation conditions.Microbial cell factories · 2016Article
- Simple phenotypic sweeps hide complex genetic changes in populations.Genome biology and evolution · 2015Article
- Characterization of mutations in the PAS domain of the EvgS sensor kinase selected by laboratory evolution for acid resistance in Escherichia coli.Molecular microbiology · 2014Article
- Ex uno plures: clonal reinforcement drives evolution of a simple microbial community.PLoS genetics · 2014Article
- Adaptation of Escherichia coli to elevated sodium concentrations increases cation tolerance and enables greater lactic acid production.Applied and environmental microbiology · 2014Article
- A case of adaptation through a mutation in a tandem duplication during experimental evolution in Escherichia coli.BMC genomics · 2013Article
- The basis of antagonistic pleiotropy in hfq mutations that have opposite effects on fitness at slow and fast growth rates.Heredity · 2013Article
- The multiplicity of divergence mechanisms in a single evolving population.Genome biology · 2012Article
- Insertion sequence-driven evolution of Escherichia coli in chemostats.Journal of molecular evolution · 2011Article
- Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in Escherichia coli.Microbial cell factories · 2011Article
- Genetic basis of growth adaptation of Escherichia coli after deletion of pgi, a major metabolic gene.PLoS genetics · 2010Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Beneficial mutations in diversifying glucose-limited Escherichia coli populations are mostly unidentified. The genome of an evolved isolate with multiple differences from that of the ancestor was fully assembled. Remarkably, a single mutation in hfq was responsible for the multiple benefits under glucose limitation through changes in at least five regulation targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.