Evidence map›Paper›PMID 20542910›Full record

ArticleNucleic acids research2010

RegPredict: an integrated system for regulon inference in prokaryotes by comparative genomics approach.

Pavel S Novichkov, Dmitry A Rodionov, Elena D Stavrovskaya, Elena S Novichkova, Alexey E Kazakov, Mikhail S Gelfand, Adam P Arkin, Andrey A Mironov, Inna Dubchak

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 135 citations in OpenAlex.

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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pavel S NovichkovLawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. psnovichkov@lbl.org
Dmitry A Rodionov
Elena D Stavrovskaya
Elena S Novichkova
Alexey E Kazakov
Mikhail S Gelfand
Adam P Arkin
Andrey A Mironov
Inna Dubchak
Lawrence Berkeley National Laboratory · US

Funding

Howard Hughes Medical Institute 55005610
6 · The paper itself

Abstract

RegPredict web server is designed to provide comparative genomics tools for reconstruction and analysis of microbial regulons using comparative genomics approach. The server allows the user to rapidly generate reference sets of regulons and regulatory motif profiles in a group of prokaryotic genomes. The new concept of a cluster of co-regulated orthologous operons allows the user to distribute the analysis of large regulons and to perform the comparative analysis of multiple clusters independently. Two major workflows currently implemented in RegPredict are: (i) regulon reconstruction for a known regulatory motif and (ii) ab initio inference of a novel regulon using several scenarios for the generation of starting gene sets. RegPredict provides a comprehensive collection of manually curated positional weight matrices of regulatory motifs. It is based on genomic sequences, ortholog and operon predictions from the MicrobesOnline. An interactive web interface of RegPredict integrates and presents diverse genomic and functional information about the candidate regulon members from several web resources. RegPredict is freely accessible at http://regpredict.lbl.gov.

Indexed as

Genome, BacterialRegulonSoftwareGenomicsInternetOperonStaphylococcaceaeSystems IntegrationUser-Computer Interface

Identifiers

PMID20542910
PMCPMC2896116
OpenAlexW2106533616

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.