Evidence map›Paper›PMID 20542380›Full record

ArticleUltramicroscopy2010

Nanometer-resolution electron microscopy through micrometers-thick water layers.

Niels de Jonge, Nicolas Poirier-Demers, Hendrix Demers, Diana B Peckys, Dominique Drouin

Abstract read
In one paragraph

Article in Ultramicroscopy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. ACS applied nano materials · 2021
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Cell culture on hydrophilicity-controlled silicon nitride surfaces.World journal of microbiology & biotechnology · 2015
    Article
  11. High-Resolution Imaging and Spectroscopy at High Pressure: A Novel Liquid Cell for the Transmission Electron Microscope.Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada · 2015
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Niels de JongeVanderbilt University Medical Center, Department of Molecular Physiology and Biophysics, Nashville, TN 37232-0615, USA. niels.de.jonge@vanderbilt.edu
Nicolas Poirier-Demers
Hendrix Demers
Diana B Peckys
Dominique Drouin

Funding

Three dimensional aberration corrected scanning transmission electron microscopyR01GM081801 · NIGMS · VANDERBILT UNIVERSITY · PI PISTON, DAVID W · 2008 to 2011
$1.4M
NIGMS NIH HHS R01 GM081801NIGMS NIH HHS R01-GM081801
6 · The paper itself

Abstract

Scanning transmission electron microscopy (STEM) was used to image gold nanoparticles on top of and below saline water layers of several micrometers thickness. The smallest gold nanoparticles studied had diameters of 1.4 nm and were visible for a liquid thickness of up to 3.3 microm. The imaging of gold nanoparticles below several micrometers of liquid was limited by broadening of the electron probe caused by scattering of the electron beam in the liquid. The experimental data corresponded to analytical models of the resolution and of the electron probe broadening as function of the liquid thickness. The results were also compared with Monte Carlo simulations of the STEM imaging on modeled specimens of similar geometry and composition as used for the experiments. Applications of STEM imaging in liquid can be found in cell biology, e.g., to study tagged proteins in whole eukaryotic cells in liquid and in materials science to study the interaction of solid:liquid interfaces at the nanoscale.

Indexed as

AnimalsElectronsEukaryotic CellsGoldHumansMicroscopy, Electron, Scanning TransmissionMonte Carlo MethodNanoparticlesNanotechnologyWaterGoldWater

Identifiers

PMID20542380
PMCPMC2917648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.