Evidence map›Paper›PMID 20542136›Full record

ReviewProgress in retinal and eye research2010

Three dimensional optical coherence tomography imaging: advantages and advances.

Michelle L Gabriele, Gadi Wollstein, Hiroshi Ishikawa, Juan Xu, Jongsick Kim, Larry Kagemann, Lindsey S Folio, Joel S Schuman

Abstract readReview
In one paragraph

Review in Progress in retinal and eye research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Low-Cost and Fast Epiretinal Membrane Detection and Quantification Based on SD-OCT.IEEE access : practical innovations, open solutions · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Drusen morphometrics on optical coherence tomography in eyes with age-related macular degeneration and normal aging.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  14. Article
  15. Functional imaging of the exposed brain.Frontiers in neuroscience · 2023
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michelle L GabrieleDepartment of Ophthalmology, UPMC Eye Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Gadi Wollstein
Hiroshi Ishikawa
Juan Xu
Jongsick Kim
Larry Kagemann
Lindsey S Folio
Joel S Schuman

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ian A Sigal · 1989 to 2026
$17.8M
Novel Glaucoma Diagnostics for Structure and Function - Renewal - 1R01EY013178 · NEI · WILLS EYE HEALTH SYSTEM · PI Joel S Schuman · 2000 to 2026
$17.5M
NEI NIH HHS P30 EY008098NEI NIH HHS P30-EY08098-23NEI NIH HHS R01 EY013178NEI NIH HHS R01-EY13178-10
6 · The paper itself

Abstract

Three dimensional (3D) ophthalmic imaging using optical coherence tomography (OCT) has revolutionized assessment of the eye, the retina in particular. Recent technological improvements have made the acquisition of 3D-OCT datasets feasible. However, while volumetric data can improve disease diagnosis and follow-up, novel image analysis techniques are now necessary in order to process the dense 3D-OCT dataset. Fundamental software improvements include methods for correcting subject eye motion, segmenting structures or volumes of interest, extracting relevant data post hoc and signal averaging to improve delineation of retinal layers. In addition, innovative methods for image display, such as C-mode sectioning, provide a unique viewing perspective and may improve interpretation of OCT images of pathologic structures. While all of these methods are being developed, most remain in an immature state. This review describes the current status of 3D-OCT scanning and interpretation, and discusses the need for standardization of clinical protocols as well as the potential benefits of 3D-OCT scanning that could come when software methods for fully exploiting these rich datasets are available clinically. The implications of new image analysis approaches include improved reproducibility of measurements garnered from 3D-OCT, which may then help improve disease discrimination and progression detection. In addition, 3D-OCT offers the potential for preoperative surgical planning and intraoperative surgical guidance.

Indexed as

Imaging, Three-DimensionalTomography, Optical CoherenceAnimalsEyeHumansOptic NerveReproducibility of ResultsRetinal DiseasesTime Factors

Identifiers

PMID20542136
PMCPMC2962728

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.