Evidence map›Paper›PMID 20541844›Full record

ArticleAtencion primaria2011

[Osteoporosis treatment with biphosphonates: Approaches to care reality].

Angel Vicente Molinero, Salvador Lou Arnal, Esteban Medina Orgaz, Sergio Muñoz Jacobo, José Antonio Ibáñez Estrella

Abstract readEnglish Abstract
In one paragraph

Article in Atencion primaria, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angel Vicente MolineroUrgencias, Hospital Royo Villanova, Zaragoza, España.
Salvador Lou Arnal
Esteban Medina Orgaz
Sergio Muñoz Jacobo
José Antonio Ibáñez Estrella

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOsteoporosis predominantly affects menopausal women and has a significant morbidity expressed as fractures. The study aimed to describe the types of bisphosphonates used to treat osteoporosis in post-menopausal women and to establish how treatment non-compliance affects the fracture rate.

designRetrospective cohort study of women on active treatment with bisphosphonates for the past five years. LOCATION: Utebo Health Centre (Zaragoza) (16,000 inhabitants) with a general medical quota of 1,890 patients).

participantsA total of 129 women who were on active treatment with bisphosphonates for five years were included. MAIN MEASURES: The distribution by drug was analysed, as well as the percentage of women who did not comply with the treatment correctly and any identified fractures.

resultsA total of 129 women on treatment were identified (13.0% of all women patients): alendronic acid (45.7%), ibandronic acid (21.7%), risedronic acid (19.4%) and alendronic acid plus cholecalciferol (13,2%). 19.4% of women stopped their treatment after at least 3 months. Thirteen hip fractures were identified.

conclusionsThe overall treatment compliance was 80.6%, Depending on the type of bisphosphonate: alendronic acid plus cholecalciferol (88.2%), risedronic acid (88.0%), alendronic acid (78.0%), ibandronic acid (75.0%). The incidence of hip fractures was similar incidence to that observed with respect to non-compliance to treatment. Lack of therapeutic compliance is common in menopausal women, and measures should be promoted to increase effectiveness as well as to make patients aware of the importance of continuing treatment.

Indexed as

Cohort StudiesDiphosphonatesDrug MonitoringFemaleHumansMenopauseOsteoporosisOsteoporotic FracturesRetrospective StudiesDiphosphonates

Identifiers

PMID20541844
PMCPMC7024967

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.