Evidence map›Paper›PMID 20541452›Full record

ReviewCurrent opinion in microbiology2010

Assembly of the flagellum and its role in cell morphogenesis in Trypanosoma brucei.

Sue Vaughan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current opinion in microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 54 citations in OpenAlex.

  1. FAZ assembly in bloodstream formMolecular biology of the cell · 2023
    Article
  2. Article
  3. Article
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  7. Article
  8. African trypanosomes.Parasites & vectors · 2019
    Article
  9. Lipidomics and anti-trypanosomatid chemotherapy.Clinical and translational medicine · 2017
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
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  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Sue VaughanSchool of Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, UK. svaughan@brookes.ac.uk
Oxford Brookes University · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Eukaryotic flagella are microtubule-based structures required for a variety of functions including cell motility and sensory perception. Most eukaryotic flagella grow out from a cell into the surrounding medium, but when the flagellum of the protozoan parasite Trypanosoma brucei exits the cell via the flagellar pocket, it is attached along the length of the cell body by a cytoskeletal structure called the flagellum attachment zone (FAZ). The exact reasons for flagellum attachment have remained elusive, but evidence is emerging that the attached flagellum plays a major role in cell morphogenesis in this organism. In this review we discuss evidence published in the past four years that is unravelling the role of the flagellum in organelle segregation, inheritance of cell shape and cytokinesis.

Indexed as

Host-Parasite InteractionsAnimalsCell ShapeCytokinesisFlagellaMorphogenesisTrypanosoma brucei bruceiTsetse Flies

Identifiers

PMID20541452
OpenAlexW2144343116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.