Evidence map›Paper›PMID 20541385›Full record

ReviewTransplantation reviews (Orlando, Fla.)2010

T regulatory cells and transplantation tolerance.

Vijay S Gorantla, Stefan Schneeberger, Gerald Brandacher, Robert Sucher, Dong Zhang, W P Andrew Lee, Xin Xiao Zheng

Abstract readReview
In one paragraph

Review in Transplantation reviews (Orlando, Fla.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Human CD8BMC immunology · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Complement regulation of T-cell alloimmunity.Seminars in nephrology · 2013
    Review
  13. Article
  14. Regulatory T cell induction, migration, and function in transplantation.Journal of immunology (Baltimore, Md. : 1950) · 2012
    Review
  15. Lymphotoxin-beta receptor blockade induces inflammation and fibrosis in tolerized cardiac allografts.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2012
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vijay S GorantlaDivision of Plastic Surgery, Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Stefan Schneeberger
Gerald Brandacher
Robert Sucher
Dong Zhang
W P Andrew Lee
Xin Xiao Zheng

Funding

A new approach to reverse onset of autoimmune diabetesR01DK067632 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ZHENG, XIN XIAO · 2004 to 2006
$886k
NIDDK NIH HHS R01 DK067632
6 · The paper itself

Abstract

Despite the development of successful immunosuppression protocols and tremendous improvement in short-term graft survival rates, the problem of chronic graft loss remains the bane of clinical transplantation. The induction and maintenance of transplantation tolerance is the "Holy Grail" of transplantation. The recent identification and characterization of regulatory T cells has opened up exciting opportunities for tolerance induction, immunotherapy, and immunomodulation in transplantation. This review focuses on current understanding of regulatory T cells and their role in transplantation tolerance.

Indexed as

Transplantation ToleranceAnimalsHumansImmunosuppressive AgentsT-Lymphocytes, RegulatoryTransplantation, HomologousTransplantation ImmunologyImmunosuppressive Agents

Identifiers

PMID20541385
PMCPMC2902703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.