ArticleCurrent opinion in biotechnology2010
Shaping up nucleic acid computation.
Article in Current opinion in biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- A gold nanoparticle conjugated single-legged DNA walker driven by catalytic hairpin assembly biosensor to detect a prokaryotic pathogen.Scientific reports · 2024Article
- Understanding the relationship between sequences and kinetics of DNA strand displacements.Nucleic acids research · 2024Article
- Article
- Encoding scheme for data storage and retrieval on DNA computers.IET nanobiotechnology · 2020Article
- A cascade reaction network mimicking the basic functional steps of adaptive immune response.Nature chemistry · 2015Article
- Using RecA protein to enhance kinetic rates of DNA circuits.Chemical communications (Cambridge, England) · 2015Article
- Article
- Design, synthesis, and application of Spinach molecular beacons triggered by strand displacement.Methods in enzymology · 2015Article
- Applications of synchrotron-based spectroscopic techniques in studying nucleic acids and nucleic acid-functionalized nanomaterials.Advanced materials (Deerfield Beach, Fla.) · 2014Review
- Exquisite allele discrimination by toehold hairpin primers.Nucleic acids research · 2014Article
- A Spinach molecular beacon triggered by strand displacement.RNA (New York, N.Y.) · 2014Article
- Nucleic acid based logical systems.Chemistry (Weinheim an der Bergstrasse, Germany) · 2014Article
- Design and application of cotranscriptional non-enzymatic RNA circuits and signal transducers.Nucleic acids research · 2014Article
- Optochemical control of deoxyoligonucleotide function via a nucleobase-caging approach.Accounts of chemical research · 2014Article
- Stacking nonenzymatic circuits for high signal gain.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Synthetic in vitro circuits.Current opinion in chemical biology · 2012Review
- Challenges and opportunities for structural DNA nanotechnology.Nature nanotechnology · 2011Review
- Dynamic DNA nanotechnology using strand-displacement reactions.Nature chemistry · 2011Review
- Molecular computing: DNA as a logic operator.Nature · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Nucleic acid-based nanotechnology has always been perceived as novel, but has begun to move from theoretical demonstrations to practical applications. In particular, the large address spaces available to nucleic acids can be exploited to encode algorithms and/or act as circuits and thereby process molecular information. In this review we not only revisit several milestones in the field of nucleic acid-based computation, but also highlight how the prospects for nucleic acid computation go beyond just a large address space. Functional nucleic acid elements (aptamers, ribozymes, and deoxyribozymes) can serve as inputs and outputs to the environment, and can act as logical elements. Into the future, the chemical dynamics of nucleic acids may prove as useful as hybridization for computation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.