ArticleStress (Amsterdam, Netherlands)2010
Repeated psychological stress-induced alterations of visceral sensitivity and colonic motor functions in mice: influence of surgery and postoperative single housing on visceromotor responses.
Article in Stress (Amsterdam, Netherlands), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
41 citing papers in PubMed, 76 citations in OpenAlex.
- Effect of Chronic Social Defeat Stress on the Small-Intestinal Environment, Including the Gut Flora, Immune System, and Mucosal Barrier Integrity.International journal of molecular sciences · 2025Article
- FAAH inhibitor URB597 shows anti-hyperalgesic action and increases brain and intestinal tissues fatty acid amides in a model of CRFNeurogastroenterology and motility · 2024Article
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- Intracerebroventricular administration of TRH Agonist, RX-77368 alleviates visceral pain induced by colorectal distension in rats.Peptides · 2024Article
- An anesthesia protocol for robust and repeatable measurement of behavioral visceromotor responses to colorectal distension in mice.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Bladder-colon chronic cross-sensitization involves neuro-glial pathways in male mice.World journal of gastroenterology · 2022Article
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- 5-HTLaboratory investigation; a journal of technical methods and pathology · 2022Article
- Involvement of toll-like receptor 5 in mouse model of colonic hypersensitivity induced by neonatal maternal separation.World journal of gastroenterology · 2022Article
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- Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation.Cell reports · 2020Article
- Fecal dysbiosis associated with colonic hypersensitivity and behavioral alterations in chronically Blastocystis-infected rats.Scientific reports · 2020Article
- Critical evaluation of animal models of visceral pain for therapeutics development: A focus on irritable bowel syndrome.Neurogastroenterology and motility · 2020Review
- Prenatal Maternal Stress Causes Preterm Birth and Affects Neonatal Adaptive Immunity in Mice.Frontiers in immunology · 2020Article
- Brain corticotropin-releasing factor signaling: Involvement in acute stress-induced visceral analgesia in male rats.Neurogastroenterology and motility · 2019Article
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- Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number.Aging · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Visceral pain modulation by chronic stress in mice has been little studied. Electromyography (EMG) recording of abdominal muscle contractions, as a proxy to the visceromotor response (VMR), requires electrode implantation and post-surgical single housing (SH) which could affect the VMR to stress. To test this hypothesis, male mice had electrode implantation surgery (S) plus SH, or no surgery and were group housed (NS-GH) or single housed (NS-SH) and exposed to either water avoidance stress (WAS, 1 h/day) or left undisturbed in their home cages for 10 days. The VMR to phasic ascending colorectal distension (CRD) was assessed before (basal) and 24 h after 10 days of WAS or no stress using a surgery-free method of intraluminal colonic pressure (ICP) recording (solid-state manometry). WAS heightened significantly the VMR to CRD at 30, 45, and 60 mmHg in S-SH vs. NS-GH, but not compared to NS-SH conscious mice. Compared to basal CRD, WAS increased VMR at 60 mmHg in the S-SH group and decreased it at 30-60 mmHg in NS-GH mice, while having no effect in NS-SH mice. The average defecation during the hour of repeated WAS over 10 days was 1.9 and 2.4 fold greater in S-SH vs. NS-GH and NS-SH mice, respectively. These data indicate that the combination of S-SH required for VMR monitoring with EMG is an important component of repeated WAS-induced post-stress visceral hypersensitivity and defecation in mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.