ReviewMedical & biological engineering & computing2010
Flexible and stretchable micro-electrodes for in vitro and in vivo neural interfaces.
Review in Medical & biological engineering & computing, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed.
- From trade-offs to translation: An interdisciplinary roadmap for neurotechnology.Science advances · 2026Review
- Advances in neuroprostheses: interfaces, materials, and applications.Nano convergence · 2026Review
- Microelectrode Arrays Technology for Brain-on-a-Chip Applications.Biosensors · 2026Review
- Review of Recent Advances in Implantable Brain-Computer Interfaces for the Restoration of Motor Function in Patients With Paralysis.Medical science monitor : international medical journal of experimental and clinical research · 2026Review
- Smart Dura: a functional artificial dura for multi-modal neural recording and modulation.Microsystems & nanoengineering · 2026Article
- Ultrasound-transparent neural interfaces for multimodal interaction.Npj flexible electronics · 2026Article
- Smart Dura: a functional artificial dura for multimodal neural recording and modulation.bioRxiv : the preprint server for biology · 2025Article
- Biomechanics characterization of an implantable ultrathin intracortical electrode through finite element method.Scientific reports · 2025Article
- Softening, Conformable, and Stretchable Conductors for Implantable Bioelectronics Interfaces.Advanced materials technologies · 2025Article
- Thin-film implants for bioelectronic medicine.MRS bulletin · 2024Review
- Architecture design and advanced manufacturing of heart-on-a-chip: scaffolds, stimulation and sensors.Microsystems & nanoengineering · 2024Review
- Biohybrid neural interfaces: improving the biological integration of neural implants.Chemical communications (Cambridge, England) · 2023Review
- Tunable Conductive Hydrogel Scaffolds for Neural Cell Differentiation.Advanced healthcare materials · 2023Article
- Cold Laser Micro-Machining of PDMS as an Encapsulation Layer for Soft Implantable Neural Interface.Micromachines · 2022Article
- Recent Advances in Stretchable and Wearable Capacitive Electrophysiological Sensors for Long-Term Health Monitoring.Biosensors · 2022Review
- The microbiota-gut-brain axis and epilepsy from a multidisciplinary perspective: Clinical evidence and technological solutions for improvement of in vitro preclinical models.Bioengineering & translational medicine · 2022Review
- Highly Stretchable Hydrogels as Wearable and Implantable Sensors for Recording Physiological and Brain Neural Signals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Engineering Tissues of the Central Nervous System: Interfacing Conductive Biomaterials with Neural Stem/Progenitor Cells.Advanced healthcare materials · 2022Review
- Highly Reliable Flexible Device with a Charge Compensation Layer.ACS applied materials & interfaces · 2022Article
- Cut wires: The Electrophysiology of Regenerated Tissue.Bioelectronic medicine · 2021Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Microelectrode arrays (MEAs) are designed to monitor and/or stimulate extracellularly neuronal activity. However, the biomechanical and structural mismatch between current MEAs and neural tissues remains a challenge for neural interfaces. This article describes a material strategy to prepare neural electrodes with improved mechanical compliance that relies on thin metal film electrodes embedded in polymeric substrates. The electrode impedance of micro-electrodes on polymer is comparable to that of MEA on glass substrates. Furthermore, MEAs on plastic can be flexed and rolled offering improved structural interface with brain and nerves in vivo. MEAs on elastomer can be stretched reversibly and provide in vitro unique platforms to simultaneously investigate the electrophysiological of neural cells and tissues to mechanical stimulation. Adding mechanical compliance to MEAs is a promising vehicle for robust and reliable neural interfaces.
Indexed as
Identifiers
20535574What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.