Evidence map›Paper›PMID 20534797›Full record

ArticleJournal of clinical microbiology2010

GeneXpert captures unstable methicillin-resistant Staphylococcus aureus prone to rapidly losing the mecA gene.

Diana E Ciardo, Sibylle Burger, Michael Payer, Christian Lee, Nadine McCallum

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Detection of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2022
    Article
  2. Review
  3. Article
  4. Characterization of the staphylococcal cassette chromosome mec insertion site in 108 isolates lacking the mecA gene and identified as methicillin-resistant Staphylococcus aureus by the Xpert MRSA assay.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diana E CiardoInstitute of Medical Microbiology, University of Zürich, Zurich, Switzerland. diana.ciardo@viollier.ch
Sibylle Burger
Michael Payer
Christian Lee
Nadine McCallum

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cefoxitin-susceptible Staphylococcus aureus strain was identified by the Cepheid GeneXpert as methicillin-resistant S. aureus (MRSA). This strain was highly unstable and rapidly lost SCCmec upon subculturing in vitro, indicating that unstable MRSA is best detected by gene amplification-based methods.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBacteriological TechniquesCefoxitinDNA, BacterialDNA FingerprintingElectrophoresis, Gel, Pulsed-FieldFemaleGenomic InstabilityHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMiddle AgedPenicillin-Binding ProteinsStaphylococcal InfectionsAnti-Bacterial AgentsBacterial ProteinsCefoxitinDNA, BacterialmecA protein, Staphylococcus aureusPenicillin-Binding Proteins

Identifiers

PMID20534797
PMCPMC2916610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.