ReviewJournal of inherited metabolic disease2010
Public health and laboratory considerations regarding newborn screening for congenital cytomegalovirus.
Review in Journal of inherited metabolic disease, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- Screening of congenital cytomegalovirus infection by real-time PCR in urine pools.European journal of pediatrics · 2012Trial
- Targeted congenital cytomegalovirus screening as part of the newborn hearing screening programme in Northeast England.European journal of pediatrics · 2025Article
- Review
- Congenital Cytomegalovirus-Related Hearing Loss.Audiology research · 2024Review
- Droplet Digital PCR (ddPCR) Does Not Enhance the Sensitivity of Detection of Cytomegalovirus (CMV) DNA in Newborn Dried Blood Spots Evaluated in the Context of Newborn Congenital CMV (cCMV) Screening.International journal of neonatal screening · 2023Article
- Diversity of the cochlear and vestibular pathologies in human temporal bones of newborns infected with cytomegalovirus.Annals of clinical pathology · 2022Article
- Diagnosing congenital Cytomegalovirus infection: don't get rid of dried blood spots.BMC infectious diseases · 2020Review
- Long-term outcomes of children with symptomatic congenital cytomegalovirus disease.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
- Screening for Congenital Cytomegalovirus After Newborn Hearing Screening: What Comes Next?Pediatrics · 2017Article
- [Risk factors for hearing impairment induced by cytomegalovirus infection].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016Article
- Universal newborn screening for congenital CMV infection: what is the evidence of potential benefit?Reviews in medical virology · 2014Review
- Review
- Congenital cytomegalovirus infection: new prospects for prevention and therapy.Pediatric clinics of North America · 2013Review
- The "silent" global burden of congenital cytomegalovirus.Clinical microbiology reviews · 2013Review
- CMV-induced Hearing Loss.Newborn (Clarksville, Md.)Article
- [Congenital Cytomegalovirus infection - still a relevant problem (based on own experience and literature)].Developmental period medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital cytomegalovirus (CMV) infection is the most common infection in newborns worldwide and causes hearing loss and other neurological disability in 15-20% of infected infants. Only about half of the hearing loss resulting from congenital CMV infection is currently detected by universal newborn hearing screening because of late-onset hearing loss. Thus, much of the hearing loss and the majority of other CMV-associated disabilities remain undetected for years after birth and are never connected to CMV infection. Congenital CMV may be appropriate to include in national newborn screening (NBS) programs because it is more common than other disorders tested for by NBS programs and is a major cause of disability. Significant obstacles to the implementation of screening for congenital CMV include the lack of a standardized, high-throughput screening test and a protocol for follow-up of CMV-infected children. Nonetheless, screening newborns for congenital CMV infection merits further consideration.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.