Evidence map›Paper›PMID 20532607›Full record

ArticleAIDS and behavior2010

Substance use in HIV-Infected women during pregnancy: self-report versus meconium analysis.

Katherine Tassiopoulos, Jennifer S Read, Susan Brogly, Kenneth Rich, Barry Lester, Stephen A Spector, Ram Yogev, George R Seage

Registry-linked trialOpen access · greenAbstract readComparative Study
In one paragraph

Article in AIDS and behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01310023 (Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women), which is not on this map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01310023 completednot on this map

Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women

TypeobservationalSponsorHarvard School of Public Health (HSPH)Ran2007 to 2025Enrolled5,169ConditionsAntiretroviral Toxicity
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Katherine TassiopoulosDepartment of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA. ktassiop@hsph.harvard.edu
Jennifer S Read
Susan Brogly
Kenneth Rich
Barry Lester
Stephen A Spector
Ram Yogev
George R Seage
Harvard University · USBrown University · USCancer Research And Biostatistics · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USLurie Children's Hospital · USUniversity of California, San Diego · USUniversity of Illinois Chicago · US

Funding

PHACS - Data and Operations CenterU01HD052102 · NICHD · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI WILLIAMS, PAIGE L · 2005 to 2019
$242.7M
Pediatric HIV/AIDS Cohort Study (PHACS): Understanding Maternal HIV Disease through Pregnancy and the Postpartum Period and its Role in Child Health OutcomesU01HD052104 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI VAN DYKE, RUSSELL B. · 2005 to 2019
$15.7M
NICHD NIH HHS U01 HD052102NICHD NIH HHS U01 HD052104NICHD NIH HHS U01 HD052104-01
6 · The paper itself

Abstract

We evaluated prenatal substance use in a cohort of 480 HIV-infected women and their uninfected children. Substance use was reported by 29%; the most common substances reported were tobacco (18%), alcohol (10%), and marijuana (7.2%). Fewer than 4% of women reported cocaine or opiate use. Substance use was more common in the first trimester (25%) than the second (17%) and third (15%) (trend p-value <0.01), and was associated with race/ethnicity, education, birthplace, age and marital status. For 264 mother/infant pairs with meconium results, sensitivity of self-report was 86% for tobacco, 80% for marijuana and 67% for cocaine. Higher discordance between self-report and urine/blood toxicology was observed for cocaine, marijuana and opiates in a non-random subset of mothers/infants with these tests. Findings suggest reasonably complete self-reporting of substance use as confirmed by meconium analysis. Illicit substance use was low and substantially less than that reported in earlier studies of HIV-infected women, but alcohol and tobacco exposure was prevalent.

Indexed as

Prenatal Exposure Delayed EffectsSelf ReportAdolescentAdultCohort StudiesFemaleHIV InfectionsHumansInfant, NewbornMeconiumMiddle AgedPregnancyPregnancy ComplicationsPregnancy TrimestersPrevalenceSocioeconomic Factors

Identifiers

PMID20532607
PMCPMC3098043
OpenAlexW2030243175

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.