ArticleAntimicrobial agents and chemotherapy2010
Genomewide analysis of divergence of antibiotic resistance determinants in closely related isolates of Acinetobacter baumannii.
Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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Who cites it
66 citing papers in PubMed.
- The (un)successful global spread ofMicrobial genomics · 2026Article
- Virulence arsenal of Acinetobacter baumannii: mechanisms driving persistence and resistance.Archives of microbiology · 2026Review
- The evolution of the multidrug-resistant and globally distributed ST2 Acinetobacter baumannii in China.BMC microbiology · 2025Article
- Phylogenomics, evolution and origin of multidrug-resistantMicrobial genomics · 2025Article
- Article
- Genomic analysis of early ST32 Acinetobacter baumannii strains recovered in US military treatment facilities reveals distinct lineages and links to the origins of the Tn6168 ampC transposon.The Journal of antimicrobial chemotherapy · 2025Article
- Manipulation of natural transformation by AbaR-type islands promotes fixation of antibiotic resistance inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Portrait of a killer: Uncovering resistance mechanisms and global spread of Acinetobacter baumannii.PLoS pathogens · 2023Article
- Clinical Resistant Strains ofAntibiotics (Basel, Switzerland) · 2023Article
- Genomic Analysis ofAntibiotics (Basel, Switzerland) · 2022Article
- Human Serum Proteins and Susceptibility ofBiomedicines · 2022Article
- Cl415, a carbapenem-resistant Acinetobacter baumannii isolate containing four AbaR4 and a new variant of AbGRI2, represents a novel global clone 2 strain.The Journal of antimicrobial chemotherapy · 2022Article
- Identification of Promoter Region Markers Associated With Altered Expression of Resistance-Nodulation-Division Antibiotic Efflux Pumps inFrontiers in microbiology · 2022Article
- Phylogenomics of two ST1 antibiotic-susceptible non-clinicalMicrobial genomics · 2021Article
- Coming from the Wild: Multidrug Resistant Opportunistic Pathogens Presenting a Primary, Not Human-Linked, Environmental Habitat.International journal of molecular sciences · 2021Review
- Antimicrobial Resistance Determinants in Genomes and Plasmids fromAntibiotics (Basel, Switzerland) · 2021Article
- Article
- Mobile Genetic Elements Harboring Antibiotic Resistance Determinants inFrontiers in microbiology · 2020Article
- Emergence, molecular mechanisms and global spread of carbapenem-resistantMicrobial genomics · 2019Review
- Insights from the revised complete genome sequences ofMicrobial genomics · 2019Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Multidrug resistance has emerged as a significant concern with infections caused by Acinetobacter baumannii. Ample evidence supports the involvement of mobile genetic elements in the transfer of antibiotic resistance genes, but the extent of variability and the rate of genetic change associated with the acquisition of antibiotic resistance have not been studied in detail. Whole-genome sequence analysis of six closely related clinical isolates of A. baumannii, including four from the same hospital, revealed extensive divergence of the resistance genotype that correlated with observed differences in antimicrobial susceptibility. Resistance genes associated with insertion sequences, plasmids, and a chromosomal resistance gene island all showed variability. The highly dynamic resistance gene repertoire suggests rapid evolution of drug resistance.
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