Evidence map›Paper›PMID 20529489›Full record

SynthesisThe British journal of general practice : the journal of the Royal College of General Practitioners2010

Quality-improvement strategies for the management of hypertension in chronic kidney disease in primary care: a systematic review.

Hugh Gallagher, Simon de Lusignan, Kevin Harris, Christopher Cates

Abstract readSystematic Review
In one paragraph

Synthesis in The British journal of general practice : the journal of the Royal College of General Practitioners, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Uncoded chronic kidney disease in primary care: a cross-sectional study of inequalities and cardiovascular disease risk management.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
    Article
  6. Improving coding and primary care management for patients with chronic kidney disease: an observational controlled study in East London.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
    Observational
  7. Review
  8. Review
  9. Electronic Health Record Patient Portals in CKD and Hypertension Management: Meaningfully Used?Clinical journal of the American Society of Nephrology : CJASN · 2015
    Article
  10. Article
  11. Implementation of a CKD checklist for primary care providers.Clinical journal of the American Society of Nephrology : CJASN · 2014
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The role of primary care in managing chronic kidney disease.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010
    Article
  17. How ready is general practice to improve quality in chronic kidney disease? A diagnostic analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hugh GallagherDivision of Community Health Sciences, HunterWing, St George's, University of London, London SW17 0RE.
Simon de Lusignan
Kevin Harris
Christopher Cates

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is a relatively recently recognised condition. People with CKD are much more likely to suffer from cardiovascular events than progress to established renal failure. Controlling systolic blood pressure should slow the progression of disease and reduce mortality and morbidity. However, no systematic review has been conducted to explore the effectiveness of quality-improvement interventions to lower blood pressure in people with CKD.

aimTo assess the effectiveness of quality-improvement interventions to reduce systolic blood pressure in people with CKD in primary care, in order to reduce cardiovascular risk and slow the progression of renal disease.

methodPapers were identified from the trial data bases of the Cochrane Effective Practice and Organisation of Care Group (EPOC) and Cochrane renal groups. In a three-round process, at least two investigators read the papers independently. Studies were initially excluded based on their abstracts, if these were not relevant to primary care. Next, full papers were read, and again excluded on relevance. Quantitative and, where this was not possible, qualitative analyses of the findings were performed.

resultsThe selected studies were usually carried out on high-risk populations including ethnic minorities. The interventions were most often led by nurses or pharmacists. Three randomised trials showed a combined effect of a reduction in systolic blood pressure of 10.50 mmHg (95% confidence interval [CI] = 5.34 to 18.41 mmHg). One non-randomised study showed a reduction in systolic blood pressure of 9.30 mmHg (95% CI = 3.01 to 15.58 mmHg).

conclusionQuality-improvement interventions can be effective in lowing blood pressure, and potentially in reducing cardiovascular risk and slowing progression in CKD. Trials are needed in low-risk populations to see if the same improvements can be achieved.

Indexed as

Outcome and Process Assessment, Health CarePrimary Health CareCardiovascular DiseasesEpidemiologic MethodsEvidence-Based MedicineHumansHypertensionRenal Insufficiency, ChronicTreatment Outcome

Identifiers

PMID20529489
PMCPMC2880767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.