Evidence map›Paper›PMID 20529376›Full record

Trial reportBMC neurology2010

Feasibility and effects of adapted cardiac rehabilitation after stroke: a prospective trial.

Ada Tang, Susan Marzolini, Paul Oh, William E McIlroy, Dina Brooks

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMC neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01067495 (Feasibility and Effects of Cardiac Rehabilitation for Individuals After Stroke), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01067495 phase1completednot on this map

Feasibility and Effects of Cardiac Rehabilitation for Individuals After Stroke

TypeinterventionalSponsorToronto Rehabilitation InstituteRan2006 to 2009Enrolled43ConditionsStrokeArmsCardiac rehabilitation
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  6. Article
  7. Review
  8. Unmet Needs for Cardiac Rehabilitation in Africa: A Perennial Gap in the Management of Individuals with Cardiac Diseases.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Review
  9. Article
  10. Inflammation-relevant microbiome signature of the stroke brain, gut, spleen, and thymus and the impact of exercise.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ada TangDepartment of Physical Therapy, University of Toronto, Canada.
Susan Marzolini
Paul Oh
William E McIlroy
Dina Brooks

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundDespite the cardiovascular etiology of stroke, exercise and risk factor modification programs akin to cardiac rehabilitation (CR) are not available. This study aimed to establish the feasibility of adapting a CR model for individuals with mild to moderate stroke disability. A secondary objective was to determine the program's effects on aerobic and walking capacity, and stroke risk factors.

methodsA repeated measures design was used with a 3-month baseline period and 6-month adapted CR intervention (n = 43, mean +/- SD age 65 +/- 12 years, 30 +/- 28 months post stroke). Feasibility was determined by the number of participants who completed the study, occurrence of adverse events and frequency, duration and intensity of exercise performed. To determine effectiveness of the program, outcomes measured included aerobic capacity (VO2peak, ventilatory threshold), 6-Minute Walk Test (6MWT) distance, and risk factors. Descriptive statistics characterized the classes attended and number and intensity of exercise sessions. Paired t-tests, one-factor repeated measures analyses of variance contrasts and chi-square analyses were used to compare changes over time.

resultsTwo participants withdrew during the baseline period. Of the remaining 41 participants who commenced the program, 38 (93%) completed all aspects. No serious adverse effects occurred. Post-intervention, VO2peak improved relative to the stable baseline period (P = 0.046) and the increase in ventilatory threshold approached significance (P = 0.062).

conclusionsCR is feasible after stroke and may be adapted to accommodate for those with a range of post-stroke disability. It is effective in increasing aerobic capacity. CR may be an untapped opportunity for stroke survivors to access programs of exercise and risk factor modification to lower future event risk.

trial registrationClinicalTrials.gov registration number: NCT01067495.

Indexed as

Cardiac RehabilitationStroke RehabilitationAdultAgedAged, 80 and overCardiovascular DiseasesExercise TherapyFeasibility StudiesFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsStrokeTime Factors

Identifiers

PMID20529376
PMCPMC2892442

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.