Evidence map›Paper›PMID 20529347›Full record

ArticleBMC neurology2010

New uses of the Migraine Screen Questionnaire (MS-Q): validation in the Primary Care setting and ability to detect hidden migraine. MS-Q in Primary Care.

Miguel J Láinez, Jesús Castillo, Manuel Domínguez, Gemma Palacios, Silvia Díaz, Javier Rejas

Open access · goldAbstract readMulticenter StudyValidation Study
In one paragraph

Article in BMC neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  5. Observational
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  9. Prevalence, Factors and Impact of Migraine on Healthcare Professionals:Sultan Qaboos University medical journal · 2025
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  17. Translation and Transcultural Validation of Migraine Screening Questionnaire (MS-Q).Medical archives (Sarajevo, Bosnia and Herzegovina) · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Miguel J LáinezDepartment of Neurology, University Hospital of Valencia, Valencia, Spain. jlaineza@meditex.es
Jesús Castillo
Manuel Domínguez
Gemma Palacios
Silvia Díaz
Javier Rejas
Pfizer (Spain) · ESHospital Central de la Defensa Gómez Ulla · ESHospital Clínico Universitario de Valencia · ESPfizer (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPC plays an important role in early diagnosis of health disorders, particularly migraine, due to the financial impact of this disease for the society and its impact on patients' quality of life. The aim of the study was to validate the self-administered MS-Q questionnaire for detection of hidden migraine in the field of primary care (PC), and to explore its use in this setting.

methodsCross-sectional, observational, and multicentre study in subjects above 18 years of age patients attending PC centers (regardless of the reason for consultation). A MS-Q score > or = 4 was considered possible migraine. Level of agreement with IHS criteria clinical diagnosis (kappa coefficient), and instrument's validity properties: sensitivity, specificity, positive (PPV) and negative (NPV) predictive values were determined. The ability of the instrument to identify possible new cases of migraine was calculated, as well as the ratio of hidden disease compared to the ratio obtained by IHS criteria.

resultsA total of 9,670 patients were included [48.9 +/- 17.2 years (mean +/- SD); 61.9% women], from 410 PC centers representative of the whole national territory. The clinical prevalence of migraine according to the IHS criteria was 24.7%, and 20.4% according to MS-Q: Kappa index of agreement 0.82 (p < 0.05). MS-Q sensitivity was 0.82 (95% CI, 0.81-0.84), specificity 0.97 (95% CI, 0.98-0.99), PPV 0.95 (95% CI, 0.94 - 0.96), and NPV 0.94 (95% CI, 0.93-0.95). No statistically significant differences were found in the percentages of patients with de novo and hidden migraine identified by MS-Q and by IHS criteria: 5.7% vs. 6.1% and 26.6% vs. 24.1%, respectively.

conclusionsThe results of the present study confirm the usefulness of the MS-Q questionnaire for the early detection and assessment of migraine in PC settings, and its ability to detect hidden migraine.

Indexed as

Surveys and QuestionnairesCross-Sectional StudiesEarly DiagnosisFeasibility StudiesFemaleHumansMaleMiddle AgedMigraine DisordersPrevalencePrimary Health CareSensitivity and SpecificitySex FactorsTime Factors

Identifiers

PMID20529347
PMCPMC2906427
OpenAlexW1968458362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.