ArticleCancer causes & control : CCC2010
Hypertension, antihypertensive medication use, and breast cancer risk in the California Teachers Study cohort.
Article in Cancer causes & control : CCC, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Association between blood pressure and risk of cancer development: a systematic review and meta-analysis of observational studies.Scientific reports · 2019Pooled it
- Hypertension and breast cancer risk: a systematic review and meta-analysis.Scientific reports · 2017Pooled it
- Use of angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers and cancer risk: a meta-analysis of observational studies.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2011Pooled it
- Endothelial dysfunction determines vascular mechanisms of metastatic progression in breast cancer.Discover oncology · 2026Review
- Association of Hypertension and Organ-Specific Cancer: A Meta-Analysis.Healthcare (Basel, Switzerland) · 2022Review
- Calcium Channel Blocker Use and the Risk for Breast Cancer: A Population-Based Nested Case-Control Study.Cancers · 2022Article
- Comprehensive molecular characterization of hypertension-related genes in cancer.Cardio-oncology (London, England) · 2022Article
- Review
- Metabolic Syndrome and Breast Cancer: Prevalence, Treatment Response, and Prognosis.Frontiers in oncology · 2021Review
- Association Between Antihypertensive Medication Use and Breast Cancer: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2021Article
- Blood pressure and risk of cancer in the European Prospective Investigation into Cancer and Nutrition.International journal of cancer · 2020Article
- Association between Thioridazine Use and Cancer Risk in Adult Patients with Schizophrenia-A Population-Based Study.Psychiatry investigation · 2018Article
- Left atrial volume in patients with HER2-positive breast cancer: One step further to predict trastuzumab-related cardiotoxicity.Clinical cardiology · 2018Article
- Use of Antihypertensive Medications and Risk of Adverse Breast Cancer Outcomes in a SEER-Medicare Population.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2017Article
- Antihypertensive drug use and breast cancer risk: a meta-analysis of observational studies.Oncotarget · 2017Article
- Modification of claims-based measures improves identification of comorbidities in non-elderly women undergoing mastectomy for breast cancer: a retrospective cohort study.BMC health services research · 2016Article
- Long-term use of calcium channel blocking drugs and breast cancer risk in a prospective cohort of US and Puerto Rican women.Breast cancer research : BCR · 2016Article
- Calcium channel blockers and cancer: a risk analysis using the UK Clinical Practice Research Datalink (CPRD).BMJ open · 2016Article
- Article
- Antihypertensive medication use and incident breast cancer in women.Breast cancer research and treatment · 2015Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundWe investigated the association between hypertension, antihypertensive (AH) medication use, and breast cancer in a large prospective study, the California Teachers Study (CTS).
methodsInformation on history of hypertension and lifetime regular use of AH medications was collected from 114,549 women in 1995-1996. Among them, 4,151 invasive breast cancers were diagnosed between 1995 and 2006. Additional information on AH use was collected from 73,742 women in 2000-2001, and 1,714 of these women were subsequently diagnosed with breast cancer. Cox proportional hazards regression was used to estimate relative risks (RR) and 95% confidence intervals (CI) for breast cancer.
resultsUse of AH medication for ≥5 years, when compared with no use, was associated with a modest increased risk of invasive breast cancer (RR = 1.18, 95%CI 1.02-1.36). This increased risk appeared to be confined to estrogen receptor (ER)-positive tumors (RR = 1.21, 95%CI 1.03-1.43) and pre-/peri-menopausal women (RR = 1.58, 95%CI 1.11-2.25).
conclusionsIncreased risk of invasive breast cancer was observed for long-term (≥5 years) AH use, and this appeared to be confined to ER + breast cancer and younger women.
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