ArticleJournal of molecular evolution2010
The evolutionary dynamics of bluetongue virus.
Article in Journal of molecular evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Global Seroprevalence of bluetongue virus in camels: a first systematic review and meta-analysis.Tropical animal health and production · 2026Pooled it
- Genome Constellations Recovered Following In Vitro Co-Infection and Serial Passage of Bluetongue Virus Serotypes 1 and 16.Viruses · 2026Article
- Molecular Epidemiological Characteristics and Genetic Evolution of Bluetongue Virus in Yunnan Province, China.Microorganisms · 2026Article
- Glycosylated NS3/NS3A protein of bluetongue virus facilitates efficient viral egress via lipid raft anchoring.Journal of virology · 2026Article
- Bluetongue's New Frontier-Are Dogs at Risk?Veterinary sciences · 2025Review
- Characterization of two novel reassortant bluetongue virus serotype 1 strains isolated from farmed white-tailed deer (Odocoileus virginianus) in Florida, USA.Virus genes · 2023Article
- Widespread Reassortment Contributes to Antigenic Shift in Bluetongue Viruses from South Africa.Viruses · 2023Article
- Retrospective Phylodynamic and Phylogeographic Analysis of the Bluetongue Virus in Tunisia.Evolutionary bioinformatics online · 2023Article
- Genetic and phylogenetic characterization of polycistronic dsRNA segment-10 of bluetongue virus isolates from India between 1985 and 2011.Virus genes · 2021Article
- Global emergence and evolutionary dynamics of bluetongue virus.Scientific reports · 2020Article
- The Genome Segments of Bluetongue Virus Differ in Copy Number in a Host-Specific Manner.Journal of virology · 2020Article
- The Genetic Diversification of a Single Bluetongue Virus Strain Using an In Vitro Model of Alternating-Host Transmission.Viruses · 2020Review
- "Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence.PLoS biology · 2020Article
- Intragenic recombination influences rotavirus diversity and evolution.Virus evolution · 2020Article
- Emergence of Southern Rice Black-Streaked Dwarf Virus in the Centuries-Old Chinese Yuanyang Agrosystem of Rice Landraces.Viruses · 2019Article
- Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot.Virus evolution · 2019Article
- Identification and genomic characterization of the first isolate of bluetongue virus serotype 5 detected in Australia.Veterinary medicine and science · 2019Article
- Identification and characterization of epizootic hemorrhagic disease virus serotype 6 in cattle co-infected with bluetongue virus in Trinidad, West Indies.Veterinary microbiology · 2019Article
- An unusually high substitution rate in transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides.PLoS pathogens · 2018Article
- Genomic analysis of bluetongue virus episystems in Australia and Indonesia.Veterinary research · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bluetongue virus (BTV) is a midge-borne member of the genus Orbivirus that causes an eponymous debilitating livestock disease of great agricultural impact and which has expanded into Europe in recent decades. Reassortment among the ten segments comprising the double-stranded (ds) RNA genome of BTV has played an important role in generating the epidemic strains of this virus in Europe. In this study, we investigated the dynamics of BTV genome segment evolution utilizing time-structured data sets of complete sequences from four segments, totalling 290 sequences largely sampled from ruminant hosts. Our analysis revealed that BTV genome segments generally evolve under strong purifying selection and at substitution rates that are generally lower (mean rates of approximately 0.5-7 x 10(-4) nucleotide substitutions per site, per year) than vector-borne positive-sense viruses with single-strand (ss) RNA genomes. These also represent the most robust estimates of the nucleotide substitution rate in a dsRNA virus generated to date. Additionally, we determined that patterns of geographic structure and times to most recent common ancestor differ substantially between each segment, including a relatively recent origin for the diversity of segment 10 within the past millennium. Together, these findings demonstrate the effect of reassortment to decouple the evolutionary dynamics of BTV genome segments.
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