Evidence map›Paper›PMID 20526430›Full record

ArticleProteomics. Clinical applications2009

The biomarker enriched proteome of autosomal dominant polycystic kidney disease cyst fluid.

Stephen B Mason, Xianyin Lai, Robert L Bacallao, Bonnie L Blazer-Yost, Vincent H Gattone, Kevin C Wang, Frank A Witzmann

Open access · greenAbstract read
In one paragraph

Article in Proteomics. Clinical applications, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Biomarkers of Kidney Disease Progression in ADPKD.Kidney international reports · 2024
    Review
  3. Article
  4. Article
  5. Proteomics of Urinary Vesicles Links Plakins and Complement to Polycystic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2016
    Article
  6. Article
  7. Article
  8. Systems biology of polycystic kidney disease: a critical review.Wiley interdisciplinary reviews. Systems biology and medicine
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stephen B MasonDepartment of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
Xianyin Lai
Robert L Bacallao
Bonnie L Blazer-Yost
Vincent H Gattone
Kevin C Wang
Frank A Witzmann
Indiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

Pathogenesis of wpk-induced Renal and Cerebral DiseaseR01DK068581 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI GATTONE, VINCENT H · 2006 to 2008
$821k
Pathogenesis of wpk-induced Renal and Cerebral DiseaseR56DK068581 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI GATTONE, VINCENT H · 2005 to 2005
$105k
NIDDK NIH HHS R01 DK068581
6 · The paper itself

Abstract

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is characterized by the development of numerous fluid-filled cysts in the kidneys of patients. We recently published our description of the proteome of renal cyst fluid in ADPKD. As a follow-up experiment, we hypothesized that the protein-bound subfraction consists of molecules of mechanistic or diagnostic interest in ADPKD. Using a manual biomarker enrichment kit, we have identified 44 distinct proteins in human cyst fluid.

Identifiers

PMID20526430
PMCPMC2880522
OpenAlexW2097474120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.