ArticleNature medicine2010
Shifting HIFs in osteoarthritis.
Article in Nature medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 101 citations in OpenAlex.
- Metabolic programming of mesenchymal stromal cells by oxygen tension directs chondrogenic cell fate.Proceedings of the National Academy of Sciences of the United States of America · 2014Trial
- Metrnl in health and disease: tissue-specific actions and signaling networks.Apoptosis : an international journal on programmed cell death · 2026Review
- DJ-1 promotes necroptosis of chondrocytes by the PTEN/PI3K-AKT signaling pathway.Cellular and molecular life sciences : CMLS · 2026Article
- Erianin protects chondrocytes against IL-1β-induced oxidative stress and ferroptosis by activating GPX4/STING signaling in osteoarthritis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Ferroptosis-mediated osteoclast-osteoblast crosstalk: signaling pathways governing bone remodeling in osteoporosis.Journal of orthopaedic surgery and research · 2025Review
- Article
- SPARCL1 promotes chondrocytes extracellular matrix degradation and inflammation in osteoarthritis via TNF/NF-κB pathway.Journal of orthopaedic translation · 2024Article
- Calycosin ameliorates osteoarthritis by regulating the imbalance between chondrocyte synthesis and catabolism.BMC complementary medicine and therapies · 2024Article
- Emerging influence of RNA post-transcriptional modifications in the synovial homeostasis of rheumatoid arthritis.Frontiers in immunology · 2024Review
- SCP2 mediates the transport of lipid hydroperoxides to mitochondria in chondrocyte ferroptosis.Cell death discovery · 2023Article
- Beyond mechanical loading: The metabolic contribution of obesity in osteoarthritis unveils novel therapeutic targets.Heliyon · 2023Review
- Exerkines and osteoarthritis.Frontiers in physiology · 2023Review
- Biomimetic hydrogel blanket for conserving and recovering intrinsic cell properties.Biomaterials research · 2022Article
- Zinc finger protein 521 attenuates osteoarthritis via the histone deacetylases 4 in the nucleus.Bioengineered · 2022Article
- Role of the Hypoxia-Inducible Factor Pathway in Normal and Osteoarthritic Meniscus and in Mice after Destabilization of the Medial Meniscus.Cartilage · 2021Article
- Human amniotic membrane modulates Wnt/β-catenin and NF-κβ signaling pathways in articular chondrocytesOsteoarthritis and cartilage open · 2021Article
- Hypoxia Regulates the Extracellular Matrix via Mitogen-Activated Protein Kinases Pathway in Cells Retrieved from the Human Intervertebral Disc.Yonsei medical journal · 2021Article
- Combination of magnesium ions and vitamin C alleviates synovitis and osteophyte formation in osteoarthritis of mice.Bioactive materials · 2021Article
- The role of indoleamine 2,3 dioxygenase 1 in the osteoarthritis.American journal of translational research · 2020Review
- Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolism.The Journal of biological chemistry · 2019Article
Corrections and comments
- Comment on
- Comment on
- Erratum issued
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.