ArticleThe European respiratory journal2011
Lean mass predicts asthma better than fat mass among females.
Article in The European respiratory journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 40 citations in OpenAlex.
- Exploring the Asthma - Obesity Link Using Advanced Imaging Techniques.Physiological research · 2025Review
- Age-related variations in trunk composition and patterns of regional bone and soft tissue changes in adult Caucasian women by DXA.Rheumatology international · 2024Article
- Application of Metabolomics in Obesity-Related Childhood Asthma Subtyping: A Narrative Scoping Review.Metabolites · 2023Article
- Adiposity and Asthma in a Nationwide Study of Children and Adults in the United States.Annals of the American Thoracic Society · 2018Article
- Article
- Association Between Obesity, Abdominal Obesity, and Adiposity and the Prevalence of Atopic Dermatitis in Young Korean Adults: the Korea National Health and Nutrition Examination Survey 2008-2010.Allergy, asthma & immunology research · 2016Article
- Chitinase 3-like-1 regulates both visceral fat accumulation and asthma-like Th2 inflammation.American journal of respiratory and critical care medicine · 2015Article
- Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study.PLoS medicine · 2014Article
- Adult-onset asthma becomes the dominant phenotype among women by age 40 years. the longitudinal CARDIA study.Annals of the American Thoracic Society · 2013Article
- Reproducibility of regional DEXA examinations of abdominal fat and lean tissue.Obesity facts · 2013Article
- Relationship between body composition, inflammation and lung function in overweight and obese asthma.Respiratory research · 2012Article
- Sex differences: implications for the obesity-asthma association.Exercise and sport sciences reviews · 2011Review
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
Abstract
The obesity phenotype associated with asthma is not known. Our objective was to define the relative contribution of various distributions of fat and lean mass to asthma prevalence. Data were obtained from 2,525 participants (including 1,422 females) who underwent dual-energy X-ray absorptiometry (DEXA) at the year 20 examination in the Coronary Artery Risk Development in Young Adults (CARDIA) cohort. Total, truncal, arm and leg distributions of fat and lean mass were adjusted to the person's height. Self-reported asthma was the outcome. Asthma among females was associated with greater total fat mass, arm fat mass, total lean mass, truncal lean mass and arm lean mass. Among males, none of these mass measures were significantly associated with asthma. Among females, the association with asthma was stronger for total lean mass than for total fat mass. Further, among various regional distributions of lean and fat mass in females, truncal lean mass was the strongest predictor. Total lean mass is more strongly associated with asthma than total fat mass among females. These findings are contrary to the popular perception that excess physiological fat drives the obesity-asthma association. Rather, we hypothesise that ectopic fat within the "lean" tissues drives this association among females.
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Registered trials
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