Evidence map›Paper›PMID 20524846›Full record

ReviewAntioxidants & redox signaling2011

Nonhuman primate models of human immunology.

Ilhem Messaoudi, Ryan Estep, Bridget Robinson, Scott W Wong

Abstract readReview
In one paragraph

Review in Antioxidants & redox signaling, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Immunophenotyping Studies in Nonhuman Primate Models.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
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  13. Article
  14. Article
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  16. Review
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  19. Social ageing can protect against infectious disease in a group-living primate.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
  20. Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ilhem MessaoudiVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon 97006, USA. messaoud@ohsu.edu
Ryan Estep
Bridget Robinson
Scott W Wong

Funding

YR 50 PROJ- ROBERTS PRIMATE ISLETP51RR000163 · NCRR · OREGON REGIONAL PRIMATE RESEARCH CENTER · PI FRUH, KLAUS J · 1985 to 2011
$140.8M
RHESUS HHV 8 HOMOLOGUE IN AIDS RELATED MALIGNANCIESR01CA075922 · NCI · OREGON REGIONAL PRIMATE RESEARCH CENTER · PI WONG, SCOTT W · 1997 to 2024
$16.7M
INTERACTIONS AT THE MICROBE/HOST INTERFACET32AI007472 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LANDFEAR, SCOTT M · 1995 to 2019
$6.7M
Anti-viral IL6 approach to mitigate KSHV-related diseaseR01CA132638 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI WONG, SCOTT W · 2008 to 2012
$3.1M
NCI NIH HHS CA132638-01NCI NIH HHS R01 CA075922NCI NIH HHS R01 CA132638NCRR NIH HHS 5P51 RR00163-47NCRR NIH HHS 5P51 RR00163-48NIAID NIH HHS T32 AI007472-12
6 · The paper itself

Abstract

Nonhuman primates have been used for biomedical research for several decades. The high level of genetic homology to humans coupled with their outbred nature has made nonhuman primates invaluable preclinical models. In this review, we summarize recent advances in our understanding of the nonhuman primate immune system, with special emphasis on studies carried out in rhesus macaque (Macaca mulatta). We highlight the utility of nonhuman primates in the characterization of immune senescence and the evaluation of new interventions to slow down the aging of the immune system.

Indexed as

Models, AnimalModels, ImmunologicalAnimalsDendritic CellsHumansImmune SystemKiller Cells, NaturalMacaca mulatta

Identifiers

PMID20524846
PMCPMC3014769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.