ArticleCell adhesion & migration
Regulation of cadherin expression in the chicken neural crest by the Wnt/β-catenin signaling pathway.
Article in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- A thermodynamic perspective on mammalian neural crest ingression.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- From neural crest migration to the onset of gangliogenesis.Current topics in developmental biology · 2025Review
- Insights into the molecular characteristics of embryonic cranial neural crest cells and their derived mesenchymal cell pools.Communications biology · 2024Article
- Time to go: neural crest cell epithelial-to-mesenchymal transition.Development (Cambridge, England) · 2022Review
- Expression atlas of avian neural crest proteins: Neurulation to migration.Developmental biology · 2022Article
- Cellular and developmental basis of orofacial clefts.Birth defects research · 2020Review
- Epithelial-to-mesenchymal transition and different migration strategies as viewed from the neural crest.Current opinion in cell biology · 2020Review
- Cranial Neural Crest Cells and Their Role in the Pathogenesis of Craniofacial Anomalies and Coronal Craniosynostosis.Journal of developmental biology · 2020Review
- Distribution of Cadherin in the Parahippocampal Area of Developing Domestic Chicken Embryos.Experimental neurobiology · 2020Article
- Cadherin-11 Is Required for Neural Crest Specification and Survival.Frontiers in physiology · 2020Article
- Review
- Chick cranial neural crest cells use progressive polarity refinement, not contact inhibition of locomotion, to guide their migration.Developmental biology · 2018Article
- CXCR4/SDF1 signalling promotes sensory neuron clusteringBiology open · 2018Article
- Atg7-Mediated Autophagy Is Involved in the Neural Crest Cell Generation in Chick Embryo.Molecular neurobiology · 2018Article
- Neural crest and cancer: Divergent travelers on similar paths.Mechanisms of development · 2017Review
- Cadherins function during the collective cell migration of Xenopus Cranial Neural Crest cells: revisiting the role of E-cadherin.Mechanisms of development · 2017Review
- Should I stay or should I go? Cadherin function and regulation in the neural crest.Genesis (New York, N.Y. : 2000) · 2017Review
- Mechanobiology of myofibroblast adhesion in fibrotic cardiac disease.Journal of cell science · 2015Review
- Regulation of cadherin expression in nervous system development.Cell adhesion & migration · 2014Review
- Article
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Authors and funding
4 authors.
Funding
Abstract
In neural crest cell development, the expression of the cell adhesion proteins cadherin-7 and cadherin-11 commences after delamination of the neural crest cells from the neuroepithelium. The canonical Wnt signaling pathway is known to drive this delamination step and is a candidate for inducing expression of these cadherins at this time. This project was initiated to investigate the role of canonical Wnt signaling in the expression of cadherin-7 and cadherin-11 by treating neural crest cells with Wnt3a ligand. Expression of cadherin-11 was first confirmed in the neural crest cells for the chicken embryo. The changes in the expression level of cadherin-7 and -11 following the treatment with Wnt3a were studied using real-time RT-PCR and immunostaining. Statistically significant upregulation in the mRNA expression of cadherin-7 and cadherin-11 and in the amount of cadherin-7 and cadherin-11 protein found in cell-cell interfaces between neural crest cells was observed in response to Wnt, demonstrating that cadherin-7 and cadherin-11 expressed by the migrating neural crest cells can be regulated by the canonical Wnt pathway.
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Registered trials
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