ArticlePlant physiology2010
The compact root architecture1 gene regulates lignification, flavonoid production, and polar auxin transport in Medicago truncatula.
Article in Plant physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 45 citations in OpenAlex.
- Biosynthesis and metabolic engineering of isoflavonoids in model plants and crops: a review.Frontiers in plant science · 2024Review
- Transcriptome-wide identification and characterization of microRNAs in diverse phases of wood formation in Populus trichocarpa.G3 (Bethesda, Md.) · 2021Article
- Flavonoid scutellarin positively regulates root length through NUTCRACKER.Plant diversity · 2021Article
- Identification of the PmWEEP locus controlling weeping traits in Prunus mume through an integrated genome-wide association study and quantitative trait locus mapping.Horticulture research · 2021Article
- A CEP Peptide Receptor-Like Kinase Regulates Auxin Biosynthesis and Ethylene Signaling to Coordinate Root Growth and Symbiotic Nodulation inThe Plant cell · 2020Article
- Methyl Salicylate Level Increase in Flax afterFrontiers in plant science · 2016Article
- Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.Scientific reports · 2015Article
- Effect of lipo-chitooligosaccharide on early growth of C4 grass seedlings.Journal of experimental botany · 2015Article
- The Control of Auxin Transport in Parasitic and Symbiotic Root-Microbe Interactions.Plants (Basel, Switzerland) · 2015Review
- Flavonoids and Auxin Transport Inhibitors Rescue Symbiotic Nodulation in the Medicago truncatula Cytokinin Perception Mutant cre1.The Plant cell · 2015Article
- Variation in Adult Plant Phenotypes and Partitioning among Seed and Stem-Borne Roots across Brachypodium distachyon Accessions to Exploit in Breeding Cereals for Well-Watered and Drought Environments.Plant physiology · 2015Article
- Local and systemic regulation of plant root system architecture and symbiotic nodulation by a receptor-like kinase.PLoS genetics · 2014Article
- Transient silencing of CHALCONE SYNTHASE during fruit ripening modifies tomato epidermal cells and cuticle properties.Plant physiology · 2014Article
- Unexpectedly low nitrogen acquisition and absence of root architecture adaptation to nitrate supply in a Medicago truncatula highly branched root mutant.Journal of experimental botany · 2014Article
- Lignin modification leads to increased nodule numbers in alfalfa.Plant physiology · 2014Article
- Metabolomics of cereals under biotic stress: current knowledge and techniques.Frontiers in plant science · 2013Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The root system architecture is crucial to adapt plant growth to changing soil environmental conditions and consequently to maintain crop yield. In addition to root branching through lateral roots, legumes can develop another organ, the nitrogen-fixing nodule, upon a symbiotic bacterial interaction. A mutant, cra1, showing compact root architecture was identified in the model legume Medicago truncatula. cra1 roots were short and thick due to defects in cell elongation, whereas densities of lateral roots and symbiotic nodules were similar to the wild type. Grafting experiments showed that a lengthened life cycle in cra1 was due to the smaller root system and not to the pleiotropic shoot phenotypes observed in the mutant. Analysis of the cra1 transcriptome at a similar early developmental stage revealed few significant changes, mainly related to cell wall metabolism. The most down-regulated gene in the cra1 mutant encodes a Caffeic Acid O-Methyl Transferase, an enzyme involved in lignin biosynthesis; accordingly, whole lignin content was decreased in cra1 roots. This correlated with differential accumulation of specific flavonoids and decreased polar auxin transport in cra1 mutants. Exogenous application of the isoflavone formononetin to wild-type plants mimicked the cra1 root phenotype, whereas decreasing flavonoid content through silencing chalcone synthases restored the polar auxin transport capacity of the cra1 mutant. The CRA1 gene, therefore, may control legume root growth through the regulation of lignin and flavonoid profiles, leading to changes in polar auxin transport.
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