Evidence map›Paper›PMID 20522543›Full record

ReviewThe Journal of biological chemistry2010

Cytosolic iron-sulfur cluster assembly (CIA) system: factors, mechanism, and relevance to cellular iron regulation.

Anil K Sharma, Leif J Pallesen, Robert J Spang, William E Walden

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Maturation strategy influences expression levels and cofactor occupancy in Fe-S proteins.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. The Role of GSH in Intracellular Iron Trafficking.International journal of molecular sciences · 2021
    Review
  9. Biogenesis of Iron-Sulfur Clusters and Their Role in DNA Metabolism.Frontiers in cell and developmental biology · 2021
    Review
  10. CIAO3 protein forms a stable ternary complex with two key players of the human cytosolic iron-sulfur cluster assembly machinery.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Fe-S Cluster Assembly in Oxymonads and Related Protists.Molecular biology and evolution · 2018
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anil K SharmaDepartment of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois 60612.
Leif J PallesenDepartment of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois 60612.
Robert J SpangDepartment of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois 60612.
William E WaldenDepartment of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois 60612. Electronic address: wwalden@uic.edu.
University of Illinois Chicago · US

Funding

REGULATION OF IRON METABOLISM GENES IN EUKARYOTESR01DK047281 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WALDEN, WILLIAM EDWARD · 1995 to 2010
$2.4M
NIDDK NIH HHS DK047281NIDDK NIH HHS R01 DK047281
6 · The paper itself

Abstract

FeS cluster biogenesis is an essential process in virtually all forms of life. Complex protein machineries that are conserved from bacteria through higher eukaryotes facilitate assembly of the FeS cofactor in proteins. In the last several years, significant strides have been made in our understanding of FeS cluster assembly and the functional overlap of this process with cellular iron homeostasis. This minireview summarizes the present understanding of the cytosolic iron-sulfur cluster assembly (CIA) system in eukaryotes, with a focus on information gained from studies in budding yeast and mammalian systems.

Indexed as

AnimalsHomeostasisHumansIronIron-Sulfur ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSulfurIronIron-Sulfur ProteinsSaccharomyces cerevisiae ProteinsSulfur

Identifiers

PMID20522543
PMCPMC2930672
OpenAlexW2027163470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.