Evidence map›Paper›PMID 20522052›Full record

ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2010

Aspects of left ventricular morphology outperform left ventricular mass for prediction of QRS duration.

Nina Hakacova, Katarina Steding, Henrik Engblom, Jane Sjögren, Charles Maynard, Olle Pahlm

Abstract read
In one paragraph

Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nina HakacovaDepartment of Clinical Physiology, Lund University Hospital, Sweden.
Katarina Steding
Henrik Engblom
Jane Sjögren
Charles Maynard
Olle Pahlm

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe knowledge of the case-specific normal QRS duration in each individual is needed when determining the onset, severity and progression of the heart disease. However, large interindividual variability even of the normal QRS duration exists. The aims of the study were to develop a model for prediction of normal QRS complex duration and to test it on healthy individuals.

methodsThe study population of healthy adult volunteers was divided into a sample for development of a prediction model (n = 63) and a testing sample (n = 30). Magnetic resonance imaging data were used to assess anatomical characteristics of the left ventricle: the angle between papillary muscles (PM(A)), the length of the left ventricle (LV(L)) and left ventricular mass (LV(M)). Twelve-lead electrocardiogram (ECG) was used for measurement of the QRS duration. Multiple linear regression analysis was used to develop a prediction model to estimate the QRS duration. The accuracy of the prediction model was assessed by comparing predicted with measured QRS duration in the test set.

resultsThe angle between PM(A) and the length of the LV(L) were statistically significant predictors of QRS duration. Correlation between QRS duration and PM(A) and LV(L) was r = 0.57, P = 0.0001 and r = 0.45, P = 0.0002, respectively. The final model for prediction of the QRS was: QRS(Predicted)= 97 + (0.35 x LV(L)) - (0.45 x PM(A)). The predicted and real QRS duration differed with median 1 ms.

conclusionsThe model for prediction of QRS duration opens the ability to predict case-specific normal QRS duration. This knowledge can have clinical importance, when determining the normality on case-specific basis.

Indexed as

AdultCardiac VolumeElectrocardiographyFemaleHeart VentriclesHumansMagnetic Resonance ImagingMaleModels, BiologicalPredictive Value of TestsReference ValuesReproducibility of Results

Identifiers

PMID20522052
PMCPMC6932018

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.