Evidence map›Paper›PMID 20521090›Full record

ArticleJournal of autism and developmental disorders2011

Brief report: Sensorimotor gating in idiopathic autism and autism associated with fragile X syndrome.

Jennifer Yuhas, Lisa Cordeiro, Flora Tassone, Elizabeth Ballinger, Andrea Schneider, James M Long, Edward M Ornitz, David Hessl

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Journal of autism and developmental disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 76 citations in OpenAlex.

  1. Emotion potentiated startle in fragile X syndrome.Journal of autism and developmental disorders · 2014
    Trial
  2. Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  3. Review
  4. Sensory Gating in Neurodevelopmental Disorders: A Scoping Review.Research on child and adolescent psychopathology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Altered Auditory Processing, Filtering, and Reactivity in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  13. Article
  14. Review
  15. Potential Involvement of Impaired BKNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jennifer YuhasMedical Investigation of Neurodevelopmental Disorders (M.I.N.D.) Institute, University of California-Davis, Medical Center, 2825 50th street, Sacramento, CA 95817, USA.
Lisa Cordeiro
Flora Tassone
Elizabeth Ballinger
Andrea Schneider
James M Long
Edward M Ornitz
David Hessl
University of California Davis Medical Center · USUniversity of California, Los Angeles · US

Funding

Genetics and Physiology of Social Anxiety in Fragile XK23MH077554 · NIMH · UNIVERSITY OF CALIFORNIA DAVIS · PI HESSL, DAVID R · 2005 to 2009
$772k
NICHD NIH HHS HD055510NIMH NIH HHS K23 MH077554NIMH NIH HHS MH77554
6 · The paper itself

Abstract

Prepulse inhibition (PPI) may useful for exploring the proposed shared neurobiology between idiopathic autism and autism caused by FXS. We compared PPI in four groups: typically developing controls (n = 18), FXS and autism (FXS+A; n = 15), FXS without autism spectrum disorder (FXS-A; n = 17), and idiopathic autism (IA; n = 15). Relative to controls, the FXS+A (p < 0.002) and FXS-A (p < 0.003) groups had impaired PPI. The FXS+A (p < 0.01) and FXS-A (p < 0.03) groups had lower PPI than the IA group. Prolonged startle latency was seen in the IA group. The differing PPI profiles seen in the FXS+A and IA indicates these groups may not share a common neurobiological abnormality of sensorimotor gating.

Indexed as

Sensory GatingAdolescentAnalysis of VarianceAutistic DisorderChildFemaleFragile X SyndromeHumansMaleReaction TimeReflex, StartleStatistics, NonparametricYoung Adult

Identifiers

PMID20521090
PMCPMC3023021
OpenAlexW2042881656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.