Evidence map›Paper›PMID 20519475›Full record

ArticleJournal of clinical microbiology2010

Ecological temporal stability of Staphylococcus aureus nasal carriage.

Olga Sakwinska, Dominique S Blanc, Catherine Lazor-Blanchet, Martine Moreillon, Marlyse Giddey, Philippe Moreillon

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  3. Novel determination ofNew microbes and new infections · 2020
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  5. Patterns and Predictors ofJournal of clinical microbiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Olga SakwinskaDepartment of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland. olga.sakwinska@unil.ch
Dominique S Blanc
Catherine Lazor-Blanchet
Martine Moreillon
Marlyse Giddey
Philippe Moreillon
University of Lausanne · CHUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We described the colonization dynamics of Staphylococcus aureus in a group of 266 healthy carriers over a period of approximately 1 year. We used precise genotyping methods, i.e., amplified fragment length polymorphism (AFLP), spa typing, and double-locus sequence typing (DLST), to detect changes in strain identity. Strain change took place rather rarely: out of 89 carriers who had initially been colonized, only 7 acquired a strain different from the original one. Approximately one-third of the carriers eliminated the colonization, and a similar number became newly colonized. Some of these events probably represent detection failure rather than genuine colonization loss or acquisition. Lower bacterial counts were associated with increased probability of eliminating the colonization. We have confirmed a high mutation rate in the spa locus: 6 out of 53 strains underwent mutation in the spa locus. There was no overall change in S. aureus genotype composition.

Indexed as

BiodiversityAdultBacterial Typing TechniquesCarrier StateColony Count, MicrobialDNA, BacterialDNA FingerprintingGenotypeHumansMaleMutationNasal MucosaPolymorphism, GeneticSequence Analysis, DNAStaphylococcal InfectionsStaphylococcal Protein ADNA, BacterialStaphylococcal Protein A

Identifiers

PMID20519475
PMCPMC2916613
OpenAlexW2098557556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.