Evidence map›Paper›PMID 20518834›Full record

ArticleInternational journal of immunogenetics2010

CCR5, RANTES and SDF-1 polymorphisms and mother-to-child HIV-1 transmission.

D A Katz, G C John-Stewart, B A Richardson, M Majiwa, J M Mabuka, B Lohman-Payne, C Farquhar

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of immunogenetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

D A KatzDepartment of Epidemiology, University of Washington, Seattle, WA 98104, USA. dkatz7@u.washington.edu
G C John-Stewart
B A Richardson
M Majiwa
J M Mabuka
B Lohman-Payne
C Farquhar

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
INTERNATIONAL TRAINING GRANT IN EPIDEMIOLOGYD43TW000007 · FIC · UNIVERSITY OF WASHINGTON · PI FARQUHAR, CAREY · 1988 to 2012
$16.3M
Urgent Versus Post-Stabilization ART in HIV+ Children with Severe Co-infectionsR01HD023412 · NICHD · UNIVERSITY OF WASHINGTON · PI Grace C. John-Stewart, DALTON CHEKOKO WAMALWA · 1987 to 2026
$12.2M
CCR5 and CXCR4 Binding Chemokines and Oral HIV InfectionR01DE014826 · NIDCR · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C · 2002 to 2005
$1.2M
Pediatric HIV-1 in Africa: Pathogenesis and ManagementK24HD054314 · NICHD · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C. · 2006 to 2016
$1.2M
Protective Immune Responses in HIV-1 Exposed InfantsK23HD041879 · NICHD · UNIVERSITY OF WASHINGTON · PI FARQUHAR, CAREY · 2002 to 2006
$628k
FIC NIH HHS D43 TW000007NIAID NIH HHS P30 AI027757NICHD NIH HHS HD023412NICHD NIH HHS K23 HD041879NICHD NIH HHS K24 HD054314NICHD NIH HHS R01 HD023412NIDCR NIH HHS DE014826NIDCR NIH HHS R01 DE014826
6 · The paper itself

Abstract

Summary Among 288 HIV-1-infected, breastfeeding women who received zidovudine prophylaxis and were followed with their infants in Nairobi, we found no associations between maternal genetic polymorphisms in CCR5 (59029G/A, 59353T/C, 59356T/C, 59402G/A), RANTES (-403G/A) and SDF-1 (3'801G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations.

Indexed as

HIV-1Infectious Disease Transmission, VerticalPolymorphism, GeneticAdolescentAdultAnti-HIV AgentsBody FluidsCervix UteriChemokine CCL5Chemokine CXCL12Cohort StudiesFemaleGenetic Predisposition to DiseaseGestational AgeHIV InfectionsHumansAnti-HIV AgentsCCL5 protein, humanChemokine CCL5Chemokine CXCL12CXCL12 protein, humanReceptors, CCR5Zidovudine

Identifiers

PMID20518834
PMCPMC2922909

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.