Evidence map›Paper›PMID 20518023›Full record

ReviewAngewandte Chemie (International ed. in English)2010

Reaction-diffusion systems in intracellular molecular transport and control.

Siowling Soh, Marta Byrska, Kristiana Kandere-Grzybowska, Bartosz A Grzybowski

Abstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Periodic Precipitation in a Confined Liquid Layer.The journal of physical chemistry letters · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Chemical Reaction Models in Synthetic Promoter Design in Bacteria.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  16. Article
  17. Article
  18. ANALYTICAL SINGULAR VALUE DECOMPOSITION FOR A CLASS OF STOICHIOMETRY MATRICES.SIAM journal on matrix analysis and applications : a publication of the Society for Industrial and Applied Mathematics · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Siowling SohDepartment of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd, Evanston, IL 60208, USA.
Marta Byrska
Kristiana Kandere-Grzybowska
Bartosz A Grzybowski

Funding

TiO2 nanocomposites for Targeted Treatment and Imaging of Prostate cancerU54CA119341 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MIRKIN, CHAD A. · 2005 to 2009
$19.9M
Microassay Systems for Diagnosis of Cancer Cell Motility and MetastasisR21CA137707 · NCI · NORTHWESTERN UNIVERSITY · PI GRZYBOWSKI, BARTOSZ ANDRZEJ · 2009 to 2011
$649k
NCI NIH HHS R21 CA137707NCI NIH HHS U54 CA119341PHS HHS 1R21A137707PHS HHS 1U54A119341-01
6 · The paper itself

Abstract

Chemical reactions make cells work only if the participating chemicals are delivered to desired locations in a timely and precise fashion. Most research to date has focused on active-transport mechanisms, although passive diffusion is often equally rapid and energetically less costly. Capitalizing on these advantages, cells have developed sophisticated reaction-diffusion (RD) systems that control a wide range of cellular functions-from chemotaxis and cell division, through signaling cascades and oscillations, to cell motility. These apparently diverse systems share many common features and are "wired" according to "generic" motifs such as nonlinear kinetics, autocatalysis, and feedback loops. Understanding the operation of these complex (bio)chemical systems requires the analysis of pertinent transport-kinetic equations or, at least on a qualitative level, of the characteristic times of the constituent subprocesses. Therefore, in reviewing the manifestations of cellular RD, we also describe basic theory of reaction-diffusion phenomena.

Indexed as

DiffusionAnimalsBiological TransportCell DivisionChemotaxisHumansIntracellular SpaceSignal Transduction

Identifiers

PMID20518023
PMCPMC3697936

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.