Evidence map›Paper›PMID 20517288›Full record

ReviewNature reviews. Gastroenterology & hepatology2010

Barrett esophagus: an update.

Rami J Badreddine, Kenneth K Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Interorgan regulation ofDevelopment (Cambridge, England) · 2017
    Article
  5. Review
  6. Toll-like receptor 9 expression in the natural history of Barrett mucosa.Virchows Archiv : an international journal of pathology · 2015
    Article
  7. Expression of SOX9 and CDX2 in nongoblet columnar-lined esophagus predicts the detection of Barrett's esophagus during follow-up.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2015
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Surveillance for gastrointestinal malignancies.World journal of gastroenterology · 2012
    Review
  13. Gastroesophageal reflux disease--from reflux episodes to mucosal inflammation.Nature reviews. Gastroenterology & hepatology · 2011
    Review
  14. Review
  15. Article
  16. Influence of obesity on the risk of esophageal disorders.Nature reviews. Gastroenterology & hepatology · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Rami J BadreddineSalem Gastroenterology Associates, 1830 S. Hawthorne Road, Winston-Salem, NC 27103, USA. badr1919@yahoo.com
Kenneth K Wang
Mayo Clinic in Florida · USSalem College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many developments have been made in the field of Barrett esophagus that have tremendous clinical implications. There are new definitions of Barrett esophagus that have had an immediate clinical impact on cancer risk and screening. Of interest is the definition by the British Society of Gastroenterology, which does not require the presence of intestinal metaplasia for a diagnosis of Barrett esophagus. Imaging techniques that allow improved visualization of intestinal metaplasia at the cellular level are now being used in clinical practice. New hypotheses elucidating the progression from squamous epithelium to intestinal metaplasia have been proposed. Indeed, the crucial role that transcription factors have in the pathogenesis of Barrett esophagus has been clarified. Improved characterization of the molecular mechanisms underlying Barrett esophagus is an incentive to undertake more basic science research in this field. Such research could also help with the development of chemoprevention strategies for this precancerous condition. This Review discusses the advances in understanding of the pathogenesis, diagnosis and treatment of Barrett esophagus.

Indexed as

Barrett EsophagusBone Morphogenetic Protein 4Catheter AblationCDX2 Transcription FactorCell Transformation, NeoplasticEpitheliumHomeodomain ProteinsHumansIntestinal MucosaPhotochemotherapyBMP4 protein, humanBone Morphogenetic Protein 4CDX2 protein, humanCDX2 Transcription FactorHomeodomain Proteins

Identifiers

PMID20517288
OpenAlexW1982648436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.