Evidence map›Paper›PMID 20516678›Full record

ArticleAmerican journal of nephrology2010

Poverty and racial disparities in kidney disease: the REGARDS study.

William M McClellan, Britt B Newsome, Leslie A McClure, George Howard, Nataliya Volkova, Paul Audhya, David G Warnock

Open access · bronzeAbstract read
In one paragraph

Article in American journal of nephrology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 83 citations in OpenAlex.

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  10. Social determinants of health and the transition from advanced chronic kidney disease to kidney failure.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
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  16. Neighborhood Social Context and Kidney Function Over Time: The Multi-Ethnic Study of Atherosclerosis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2019
    Article
  17. Social Determinants of CKD Hotspots.Seminars in nephrology · 2019
    Review
  18. Article
  19. Observational
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

William M McClellanRenal Division, Emory University School of Medicine, Atlanta, GA 30322, USA. wmcclel@sph.emory.edu
Britt B Newsome
Leslie A McClure
George Howard
Nataliya Volkova
Paul Audhya
David G Warnock
Emory University · USUniversity of Alabama at Birmingham · USAmgen (United States) · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

unlabelledThere are pronounced disparities among black compared to white Americans for risk of end-stage renal disease. This study examines whether similar relationships exist between poverty and racial disparities in chronic kidney disease (CKD) prevalence.

methodsWe studied 22,538 participants in the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort study. We defined individual poverty as family income below USD 15,000 and a neighborhood as poor if 25% or more of the households were below the federal poverty level.

resultsAs the estimated glomerular filtration rate (GFR) declined from 50-59 to 10-19 ml/min/ 1.73 m2, the black:white odds ratio (OR) for impaired kidney function increased from 0.74 (95% CI 0.66, 0.84) to 2.96 (95% CI 1.96, 5.57). Controlling for individual income below poverty, community poverty, demographic and comorbid characteristics attenuated the black:white prevalence to an OR of 0.65 (95% CI 0.57, 0.74) among individuals with a GFR of 59-50 ml/min/1.73 m2 and an OR of 2.21 (95% CI 1.25, 3.93) among individuals with a GFR between 10 and 19 ml/min/ 1.73 m2.

conclusionHousehold, but not community poverty, was independently associated with CKD and attenuated but did not fully account for differences in CKD prevalence between whites and blacks.

Indexed as

AgedAged, 80 and overBlack or African AmericanComorbidityCreatinineFemaleGlomerular Filtration RateHumansIncomeMaleMiddle AgedPovertyPrevalenceRenal Insufficiency, ChronicRisk FactorsSeverity of Illness IndexCreatinine

Identifiers

PMID20516678
PMCPMC2914392
OpenAlexW2069702801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.