Trial reportThe American journal of psychiatry2010
Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction.
Trial report in The American journal of psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00052091 (PST in Geriatric Depression With Executive Dysfunction), which is not on this map. Cited by 110 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PST in Geriatric Depression With Executive Dysfunction
Who cites it
110 citing papers in PubMed, 6 syntheses or guidelines pooled it, 272 citations in OpenAlex.
- Non-pharmacological interventions for depression/anxiety in older adults with physical comorbidities affecting functioning: systematic review and meta-analysis.International psychogeriatrics · 2019Pooled it
- A Meta-Analysis of Executive Dysfunction and Antidepressant Treatment Response in Late-Life Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016Pooled it
- Pooled it
- Managing depression in older age: psychological interventions.Maturitas · 2014Pooled it
- Psychological treatments for depression and anxiety in dementia and mild cognitive impairment.The Cochrane database of systematic reviews · 2014Pooled it
- Psychosocial interventions for late-life major depression: evidence-based treatments, predictors of treatment outcomes, and moderators of treatment effects.The Psychiatric clinics of North America · 2011Pooled it
- Association of depressive disorders and dementia with mortality among older people with hip fracture.BMC geriatrics · 2023Trial
- Modifiable predictors of suicidal ideation during psychotherapy for late-life major depression. A machine learning approach.Translational psychiatry · 2021Trial
- Modifiable predictors of nonresponse to psychotherapies for late-life depression with executive dysfunction: a machine learning approach.Molecular psychiatry · 2021Trial
- Comparing the streamlined psychotherapy "Engage" with problem-solving therapy in late-life major depression. A randomized clinical trial.Molecular psychiatry · 2021Trial
- Effect of Telehealth Treatment by Lay Counselors vs by Clinicians on Depressive Symptoms Among Older Adults Who Are Homebound: A Randomized Clinical Trial.JAMA network open · 2020Trial
- Resting State Functional Connectivity and Outcomes of Psychotherapies for Late-Life Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2020Trial
- Two Interventions for PatientsWith Major Depression and Severe Chronic Obstructive Pulmonary Disease: Impact on Quality of Life.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019Trial
- Improving late life depression and cognitive control through the use of therapeutic video game technology: A proof-of-concept randomized trial.Depression and anxiety · 2017Trial
- Therapeutic relationship in the treatment of geriatric depression with executive dysfunction.Journal of affective disorders · 2017Trial
- Two Behavioral Interventions for Patients with Major Depression and Severe COPD.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016Trial
- The impact of executive function on response to cognitive behavioral therapy in late-life depression.International journal of geriatric psychiatry · 2016Trial
- Clinical Case Management versus Case Management with Problem-Solving Therapy in Low-Income, Disabled Elders with Major Depression: A Randomized Clinical Trial.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016Trial
- Problem-Solving Therapy Reduces Suicidal Ideation In Depressed Older Adults with Executive Dysfunction.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016Trial
- Relationship Between Cerebrovascular Risk, Cognition, and Treatment Outcome in Late-Life Psychotic Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015Trial
50 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThe purpose of this study was to determine whether problem-solving therapy is an effective treatment in older patients with depression and executive dysfunction, a population likely to be resistant to antidepressant drugs.
methodParticipants were adults age 60 and older with major depression and executive dysfunction. Problem-solving therapy was modified to be accessible to this population. Participants were randomly assigned to 12 weekly sessions of problem-solving therapy or supportive therapy and assessed at weeks 3, 6, 9, and 12.
resultsOf the 653 individuals referred for this study, 221 met selection criteria and were enrolled in the study. Reduction of depressive symptom severity was comparable for the two treatment groups during the first 6 weeks of treatment, but at weeks 9 and 12 the problem-solving therapy group had a greater reduction in symptom severity, a greater response rate, and a greater remission rate than the supportive therapy group (response rates at week 9: 47.1% and 29.3%; at week 12:56.7% and 34.0%; remission rates at week 9: 37.9% and 21.7%; at week 12: 45.6% and 27.8%). Problem-solving therapy yielded one additional response or remission over supportive therapy for every 4.4-5.6 patients by the end of the trial.
conclusionsThese results suggest that problem-solving therapy is effective in reducing depressive symptoms and leading to treatment response and remission in a considerable number of older patients with major depression and executive dysfunction. The clinical value of this finding is that problem-solving therapy may be a treatment alternative in an older patient population likely to be resistant to pharmacotherapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.