ReviewCold Spring Harbor perspectives in biology2010
Use of forward genetics to discover novel regulators of NF-kappaB.
Review in Cold Spring Harbor perspectives in biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Discovery and characterization of anti-cancer peptides from a random peptide library.PloS one · 2024Article
- Caspase-3 cleaved p65 fragment dampens NF-κB-mediated anti-apoptotic transcription by interfering with the p65/RPS3 interaction.FEBS letters · 2015Article
- NF-κB: Regulation by Methylation.Cancer research · 2015Review
- Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis.PloS one · 2014Article
- Identification of an N-terminal truncation of the NF-κB p65 subunit that specifically modulates ribosomal protein S3-dependent NF-κB gene expression.The Journal of biological chemistry · 2012Article
- Lysine methylation of promoter-bound transcription factors and relevance to cancer.Cell research · 2011Article
- Article
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Authors and funding
2 authors.
Funding
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Abstract
Forward and reverse genetic experiments have both played important roles in revealing critical aspects of mammalian signal transduction pathways in cell culture experiments. Only recently have we begun to comprehend the depth, breadth, and complexity of these pathways and of their interrelationships. Here, we summarize successful examples in which different forward genetic approaches have led to novel discoveries in NF-kappaB signaling. We believe that forward genetics will continue to play an irreplaceable role in advancing our understanding of the complexities of the pathways that regulate the functions of this key transcription factor.
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