Evidence map›Paper›PMID 20515766›Full record

ReviewFrontiers in bioscience (Elite edition)2010

Gaseous neurotransmitters and their role in anapyrexia.

Luiz G S Branco, Kenia C Bicego, Evelin C Carnio, Quentin J Pittman

Abstract readReview
In one paragraph

Review in Frontiers in bioscience (Elite edition), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Does Hypoxia Decrease the Metabolic Rate?Frontiers in endocrinology · 2018
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luiz G S BrancoDental School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil. branco@forp.usp.br
Kenia C Bicego
Evelin C Carnio
Quentin J Pittman

Funding

CIHR 67143
6 · The paper itself

Abstract

Mammals keep their body temperature (Tb) relatively constant even under a wide range of ambient temperature variation. However, in some particular situations it may be beneficial to increase or to decrease Tb. For instance, under hypoxic conditions, a regulated drop in Tb (anapyrexia) takes place which has been reported to be crucial for survival in a number of different species. This review highlights major advances in the research about nitric oxide (NO) and carbon monoxide (CO- where data are relatively less abundant), before focusing on the role played by these gaseous neuromediators in thermoregulation, under the conditions of euthermia and anapyrexia. Available data are consistent with the notion that both NO and CO, acting on the CNS, participate in thermoregulation, with NO decreasing Tb and CO increasing it. However further studies are required before definitive conclusions can be made as to their physiological mechanisms of action.

Indexed as

GasesAnimalsBody Temperature RegulationHeme Oxygenase (Decyclizing)Neurotransmitter AgentsNitric OxideRatsGasesHeme Oxygenase (Decyclizing)Neurotransmitter AgentsNitric Oxide

Identifiers

PMID20515766
PMCPMC3554786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.