ReviewCurrent hypertension reports2010
Vascular effects of antihypertensive drug therapy.
Review in Current hypertension reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Maintenance over Time of the Effect Produced by Esmolol on the Structure and Function of Coronary Arteries in Hypertensive Heart Diseases.Antioxidants (Basel, Switzerland) · 2022Article
- Dronedarone induces regression of coronary artery remodeling related to better global antioxidant status.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Vascular Aging and Disease of the Small Vessels.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2019Review
- Article
- Impact of a Multichannel Blocker in Attenuating Intramyocardial Artery Remodeling in Hypertensive Rats through Increased Nitric Oxide Bioavailability.BioMed research international · 2019Article
- Early regression of coronary artery remodeling with esmolol and DDAH/ADMA pathway in hypertensive rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
- TLR4 as a possible key regulator of pathological vascular remodeling by Ang II receptor activation.Hypertension research : official journal of the Japanese Society of Hypertension · 2015Article
- Interactions between macro- and micro-circulation: are they relevant?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015Review
- Short-term esmolol improves coronary artery remodeling in spontaneously hypertensive rats through increased nitric oxide bioavailability and superoxide dismutase activity.BioMed research international · 2014Article
- Differential regulation of nitric oxide synthase function in aorta and tail artery from 5/6 nephrectomized rats.Physiological reports · 2013Article
- Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer.Radiation oncology (London, England) · 2013Article
- Individualization of antihypertensive drug treatment.Diabetes care · 2013Article
- Treatment of arterial remodeling in essential hypertension.Current hypertension reports · 2013Review
- Appropriateness of cardiovascular care in elderly adult cancer survivors.Medical oncology (Northwood, London, England) · 2013Article
- Plasticity of TRPV1-Expressing Sensory Neurons Mediating Autonomic Dysreflexia Following Spinal Cord Injury.Frontiers in physiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Hypertension is associated with structural and functional alterations in the vasculature that lead to hemodynamic disturbances and target organ damage. The benefit of reducing blood pressure on risk reduction is well established. Antihypertensive drugs partially correct hypertensive vascular changes by a number of mechanisms, but their influence may vary in different vascular beds. Recently, combinations of drugs with complementary or synergistic effects have shown favorable effects on the vasculature; these combinations may contribute to risk reduction and improve outcomes in the future. Clinical trial evidence has shown an improvement in morbidity and mortality indicators that could be related to vascular effects of antihypertensive drugs, but this effect needs to be proven in future long-term prospective studies involving simultaneous evaluation of small-artery and large-artery properties.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.