ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2010
Development of the AGREE II, part 1: performance, usefulness and areas for improvement.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 191 papers, 56 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
191 citing papers in PubMed, 56 syntheses or guidelines pooled it.
- Improvement of Clinical Practice Guideline Appraisal by Human Experts and AI Agents by Using Structured Guidance: Systematic Review, Meta-Analysis, and Validation Study.Journal of medical Internet research · 2026Pooled it
- Inconsistencies in recommendations for the preventive management of pre-eclampsia and quality assessment of international guidelines: a systematic review.BMC pregnancy and childbirth · 2026Pooled it
- Methodological quality and clinical applicability of long COVID guidelines and scientific statements: a systematic review using AGREE II and AGREE-REX.Frontiers in public health · 2026Pooled it
- Current guidelines in hypertension management with special focus on management of extremely high blood pressure: a systematic review.BMC cardiovascular disorders · 2025Pooled it
- Methodological Quality of Pulmonary Arterial Hypertension Treatment Evidence-Based Guidelines: A Systematic Review Using the AGREE II and AGREE REX Tools.Cardiovascular drugs and therapy · 2025Pooled it
- Rigour of development of European Society of Cardiology, American College of Cardiology and American Heart Association guidelines over a 12-year period (2013-2024): a systematic review of guidelines.European heart journal. Quality of care & clinical outcomes · 2025Pooled it
- Management of Diabetes and Hyperglycemia in the Hospital: A Systematic Review of Clinical Practice Guidelines.Diabetes care · 2025Pooled it
- Guideline recommendations on the assessment and management of awake airway intubation: a systematic review.BMC anesthesiology · 2025Pooled it
- Quality appraisal of clinical practice guidelines for attention deficit hyperactivity disorder: a systematic review using the appraisal of guidelines for research and evaluation (AGREE II) instrument.Frontiers in psychiatry · 2025Pooled it
- Pooled it
- Incorporating Social Determinants of Health in Infectious Disease Models: A Systematic Review of Guidelines.Medical decision making : an international journal of the Society for Medical Decision Making · 2024Pooled it
- Clinical practice guidelines and expert consensus statements on rehabilitation for patients with COVID-19: a systematic review.BMJ open · 2024Pooled it
- Evidence-based clinical practice guidelines for the management of acute ankle injuries according to: a PRISMA systematic review and quality appraisal with AGREE II.BMC musculoskeletal disorders · 2024Pooled it
- Pooled it
- Management of Inpatient Elevated Blood Pressures : A Systematic Review of Clinical Practice Guidelines.Annals of internal medicine · 2024Pooled it
- What are the core recommendations for rheumatoid arthritis care? Systematic review of clinical practice guidelines.Clinical rheumatology · 2023Pooled it
- Complementary and alternative medicine mention and recommendations in inflammatory bowel disease guidelines: systematic review and assessment using AGREE II.BMC complementary medicine and therapies · 2023Pooled it
- Assessment of the Quality of Current American Dental Association Clinical Practice Guidelines.JDR clinical and translational research · 2023Pooled it
- Canadian Cardiovascular Harmonized National Guideline Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2022 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Guideline
- Neck pain clinical practice guidelines: a systematic review of the quality and quantity of complementary and alternative medicine recommendations.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Pooled it
131 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundWe undertook research to improve the AGREE instrument, a tool used to evaluate guidelines. We tested a new seven-point scale, evaluated the usefulness of the original items in the instrument, investigated evidence to support shorter, tailored versions of the tool, and identified areas for improvement.
methodWe report on one component of a larger study that used a mixed design with four factors (user type, clinical topic, guideline and condition). For the analysis reported in this article, we asked participants to read a guideline and use the AGREE items to evaluate it based on a seven-point scale, to complete three outcome measures related to adoption of the guideline, and to provide feedback on the instrument's usefulness and how to improve it.
resultsGuideline developers gave lower-quality ratings than did clinicians or policy-makers. Five of six domains were significant predictors of participants' outcome measures (p < 0.05). All domains and items were rated as useful by stakeholders (mean scores > 4.0) with no significant differences by user type (p > 0.05). Internal consistency ranged between 0.64 and 0.89. Inter-rater reliability was satisfactory. We received feedback on how to improve the instrument.
interpretationQuality ratings of the AGREE domains were significant predictors of outcome measures associated with guideline adoption: guideline endorsements, overall intentions to use guidelines, and overall quality of guidelines. All AGREE items were assessed as useful in determining whether a participant would use a guideline. No clusters of items were found more useful by some users than others. The measurement properties of the seven-point scale were promising. These data contributed to the refinements and release of the AGREE II.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.