ArticleMolecular cell2010
Cdks regulate autophagy via Vps34.
Article in Molecular cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
- Kinases Involved in Both Autophagy and Mitosis.International journal of molecular sciences · 2017Review
- Autophagic flux is highly active in early mitosis and differentially regulated throughout the cell cycle.Oncotarget · 2016Article
Corrections and comments
- Comment on
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this issue of Molecular Cell, Junying Yuan's group has shown that cyclin-dependent kinases phosphorylate and inactivate Vps34, resulting in autophagy downregulation (Furuya et al., 2010). This phenomenon can explain how autophagy is controlled during mitosis, and has potential importance for understanding the pathogenesis of Alzheimer's disease and cancers.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.