Evidence map›Paper›PMID 20513022›Full record

ArticleThe Laryngoscope2010

Model for estimating the threshold mechanical stability of structural cartilage grafts used in rhinoplasty.

Allison Zemek, Rohit Garg, Brian J F Wong

Abstract read
In one paragraph

Article in The Laryngoscope, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Keylock system: a new, strong, and easy mechanism for nasal reconstruction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2015
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Allison ZemekDepartment of Otolaryngology-Head and Neck Surgery, Division of Facial Plastic Surgery, University of California Irvine, Irvine, California, USA.
Rohit Garg
Brian J F Wong
University of California, Irvine · US

Funding

WOUND MIGRATION FORCE MONITORINGP41RR001192 · NCRR · UNIVERSITY OF CALIFORNIA-IRVINE · PI LYUBOVITSKY, JULIA · 1985 to 2011
$14.2M
Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY J · 2012 to 2017
$7.0M
Analysis of thermoviscoelastic behavior in cartilageR03DC005572 · NIDCD · UNIVERSITY OF CALIFORNIA IRVINE · PI WONG, BRIAN · 2003 to 2005
$248k
NCRR NIH HHS P41 RR001192NCRR NIH HHS RR-01192NIBIB NIH HHS P41 EB015890NIDCD NIH HHS DC005572NIDCD NIH HHS R03 DC005572PHS HHS D00170
6 · The paper itself

Abstract

objectives/hypothesisCharacterizing the mechanical properties of structural cartilage grafts used in rhinoplasty is valuable because softer engineered tissues are more time- and cost-efficient to manufacture. The aim of this study is to quantitatively identify the threshold mechanical stability (e.g., Young's modulus) of columellar, L-strut, and alar cartilage replacement grafts. STUDY

designDescriptive, focus group survey.

methodsTen mechanical phantoms of identical size (5 x 20 x 2.3 mm) and varying stiffness (0.360 to 0.85 MPa in 0.05 MPa increments) were made from urethane. A focus group of experienced rhinoplasty surgeons (n = 25, 5 to 30 years in practice) were asked to arrange the phantoms in order of increasing stiffness. Then, they were asked to identify the minimum acceptable stiffness that would still result in favorable surgical outcomes for three clinical applications: columellar, L-strut, and lateral crural replacement grafts. Available surgeons were tested again after 1 week to evaluate intra-rater consistency.

resultsFor each surgeon, the threshold stiffness for each clinical application differed from the threshold values derived by logistic regression by no more than 0.05 MPa (accuracy to within 10%). Specific thresholds were 0.56, 0.59, and 0.49 MPa for columellar, L-strut, and alar grafts, respectively. For comparison, human nasal septal cartilage is approximately 0.8 MPa.

conclusionsThere was little inter- and intra-rater variation of the identified threshold values for adequate graft stiffness. The identified threshold values will be useful for the design of tissue-engineered or semisynthetic cartilage grafts for use in structural nasal surgery.

Indexed as

Prostheses and ImplantsBiomechanical PhenomenaCartilageElasticityFocus GroupsHumansLogistic ModelsMaterials TestingModels, BiologicalPolyurethanesRhinoplastyTissue EngineeringPolyurethanes

Identifiers

PMID20513022
PMCPMC3970717
OpenAlexW2147393754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.