ArticlePathology oncology research : POR2011
Monolobar hepatobiliary fibropolycystic disease.
Article in Pathology oncology research : POR, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- A rare encounter - Unveiling the mysteries of biliary hamartoma: A case report.International journal of surgery case reports · 2024Article
- A Retrospective Case Control Study of Ductal Plate Malformation-like Features in Consecutive 200 Autopsies.Pathology oncology research : POR · 2018Article
- Human ductal plate and its derivatives express antigens of cholangiocellular, hepatocellular, hepatic stellate/progenitor cell, stem cell, and neuroendocrine lineages, and proliferative antigens.Experimental biology and medicine (Maywood, N.J.) · 2017Article
- Bile Duct Hamartoma Mimicking Metastatic Cholangiocarcinoma.Journal of gastrointestinal cancer · 2017Article
- Hepatobiliary cystadenocarcinoma of the liver with features of ductal plate malformations.Journal of gastrointestinal cancer · 2015Article
- Ductal plate in hepatoblasts in human fetal livers: I. ductal plate-like structures with cytokeratins 7 and 19 are occasionally seen within human fetal hepatoblasts.International journal of clinical and experimental pathology · 2013Article
- Combined hepatocellular-cholangiocarcinoma with stem cell features, ductal plate malformation subtype: a case report and proposal of a new subtype.International journal of clinical and experimental pathology · 2013Article
- Human fetal ductal plate revisited: II. MUC1, MUC5AC, and MUC6 are expressed in human fetal ductal plate and MUC1 is expressed also in remodeling ductal plate, remodeled ductal plate and mature bile ducts of human fetal livers.International journal of clinical and experimental pathology · 2013Article
- Congenital hepatic fibrosis and autosomal recessive polycystic kidney disease.Journal of pediatric gastroenterology and nutrition · 2012Review
- Monosegmental hepatobiliary fibropolycystic disease mimicking a mass: report of three cases.Korean journal of radiologyArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We herein report a case of monolobar hepatobiliary fibropolycystic disease. A 75-year-old woman presented with heartburn. Imaging modalities including US, CT, and MRI revealed marked atrophy and multiple biliary cysts of the hepatic left lobe. The hepatic right lobe was normal. ERCP and bile duct endoscopy revealed anomalous pancreaticobiliary union, choledochal dilation, dilation of left intrahepatic bile ducts, and small choledochal non-invasive adenocarcinoma. Polycystic kidney diseases were absent. The patient underwent pancreatico-duodenectomy and extended hepatic left lobectomy. Grossly, the hepatic left lobe was markedly atrophic, and studded with numerous biliary cysts. The left intrahepatic bile ducts were dilated (Caroli's disease) and the common bile duct showed type I choledochal dilation. The right hepatic lobe was normal. Histologically, the hepatic left lobe was replaced by fibroelastosis. The intrahepatic bile ducts showed ductal plate malformation such as irregular contours, invaginations, and protrusions. The numerous biliary cysts also showed ductal plate malformation. There were numerous persistent ductal plates and microhamartomas. Many hyalinized destructive biliary cysts and ductal plates were recognized. The liver parenchyma was scant and free of hepatocellular malformations. The portal veins showed old obliterative portal thrombosis. The right hepatic lobe was normal. Immunohistochemically, the biliary cells were positive for cytokeratin 7, 8, 18 and 19, and MUC6 and CD10, but negative for MUC2 and MUC5AC. The biliary cysts, persistent ductal plate, and microhamartomas were positive for fetal apomucin antigen MUC1.
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