Evidence map›Paper›PMID 20512289›Full record

ArticleSao Paulo medical journal = Revista paulista de medicina2009

C-reactive protein is not a useful indicator for infection in surgical intensive care units.

Domingos Dias Cicarelli, Joaquim Edson Vieira, Fábio Ely Martins Benseñor

Open access · diamondAbstract read
In one paragraph

Article in Sao Paulo medical journal = Revista paulista de medicina, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Antimicrobial strategies for ureteral stent removal after radical cystectomy: a comparative cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. [CD64 index as a marker of infection in patients with postoperative fever].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2018
    Observational
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Domingos Dias CicarelliDepartment of Surgery, Hospital das Clínicas da Faculdade, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil. dcicarelli@uol.com.br
Joaquim Edson Vieira
Fábio Ely Martins Benseñor
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CONTEXT AND

objectiveC-reactive protein (CRP) is commonly used as a marker for inflammatory states and for early identification of infection. This study aimed to investigate CRP as a marker for infection in patients with postoperative septic shock. DESIGN AND

settingProspective, single-center study, developed in a surgical intensive care unit at Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo.

methodsThis study evaluated 54 patients in the postoperative period, of whom 29 had septic shock (SS group) and 25 had systemic inflammatory response syndrome (SIRS group). All of the patients were monitored over a seven-day period using the Sequential Organ Failure Assessment (SOFA) score and daily CRP and lactate measurements.

resultsThe daily CRP measurements did not differ between the groups. There was no correlation between CRP and lactate levels and the SOFA score in the groups. We observed that the plasma CRP concentrations were high in almost all of the patients. The patients presented an inflammatory state postoperatively in response to surgical aggression. This could explain the elevated CRP measurements, regardless of whether the patient was infected or not.

conclusionsThis study did not show any correlation between CRP and infection among patients with SIRS and septic shock during the early postoperative period.

Indexed as

Analysis of VarianceBiomarkersC-Reactive ProteinCritical CareFemaleHumansLactic AcidMaleMiddle AgedMultiple Organ FailurePostoperative ComplicationsProspective StudiesShock, SepticSurgical Wound InfectionSystemic Inflammatory Response SyndromeBiomarkersC-Reactive ProteinLactic Acid

Identifiers

PMID20512289
PMCPMC11149671
OpenAlexW2061875089

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.