ReviewJournal of bacteriology2010
Nooks and crannies in type VI secretion regulation.
Review in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
93 citing papers in PubMed, 151 citations in OpenAlex.
- The divergentMicrobiology (Reading, England) · 2026Article
- Phenotypic heterogeneity optimizes trade-offs during adaptive deployment of the type VI secretion system.PLoS biology · 2026Article
- Deciphering theJournal of bacteriology · 2025Review
- Article
- Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance.Nature communications · 2025Article
- Article
- Article
- Transcriptome profiling of type VI secretion system core geneMicrobiology spectrum · 2024Article
- Regulation of type VI secretion systems at the transcriptional, posttranscriptional and posttranslational level.Microbiology (Reading, England) · 2023Review
- A subcellular biochemical model for T6SS dynamics reveals winning competitive strategies.PNAS nexus · 2023Article
- Paradoxical Activation of a Type VI Secretion System Phospholipase Effector by Its Cognate Immunity Protein.Journal of bacteriology · 2023Article
- Diversity of the type VI secretion systems in theMicrobial genomics · 2023Article
- Transcriptional organization and regulation of theMicrobiology (Reading, England) · 2023Article
- High-resolution spatial and genomic characterization of coral-associated microbial aggregates in the coralScience advances · 2022Article
- CqsA/LuxS-HapR Quorum sensing circuit modulates type VI secretion system VflT6SS2 inEmerging microbes & infections · 2021Article
- Putative RNA Ligase RtcB Affects the Switch between T6SS and T3SS inInternational journal of molecular sciences · 2021Article
- Activation of the Type VI Secretion System in the Squid SymbiontJournal of bacteriology · 2021Article
- The evolution of strategy in bacterial warfare via the regulation of bacteriocins and antibiotics.eLife · 2021Article
- The evolution of tit-for-tat in bacteria via the type VI secretion system.Nature communications · 2020Article
- RovC - a novel type of hexameric transcriptional activator promoting type VI secretion gene expression.PLoS pathogens · 2020Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type VI secretion systems (T6SS) are macromolecular, transenvelope machines encoded within the genomes of most Gram-negative bacteria, including plant, animal, and human pathogens, as well as soil and environmental isolates. T6SS are involved in a broad variety of functions: from pathogenesis to biofilm formation and stress sensing. This large array of functions is reflected by a vast diversity of regulatory mechanisms: repression by histone-like proteins and regulation by quorum sensing, transcriptional factors, two-component systems, alternative sigma factors, or small regulatory RNAs. Finally, T6SS may be produced in an inactive state and are turned on through the action of a posttranslational cascade involving phosphorylation and subunit recruitment. The current data reviewed here highlight how T6SS have been integrated into existing regulatory networks and how the expression of the T6SS loci is precisely modulated to adapt T6SS production to the specific needs of individual bacteria.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.