ReviewRheumatic diseases clinics of North America2010
Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritis.
Review in Rheumatic diseases clinics of North America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Genetic markers as therapeutic target in rheumatoid arthritis: A game changer in clinical therapy?Rheumatology international · 2016Review
- Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy.Arthritis research & therapy · 2015Review
- Ultrasonographic assessment of enthesitis in HLA-B27 positive patients with rheumatoid arthritis, a matched case-only study.PloS one · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The purpose of this article is to place these genetic discoveries in the context of current and future therapeutic strategies for patients with RA. More specifically, this article focuses on (1) a brief overview of genetic studies, (2) human genetics as an approach to identify the Achilles heel of disease pathways, (3) humans as the model organism for functional studies of human mutations, (4) pharmacogenetic studies to gain insight into the mechanism of action of drugs, and (5) next-generation patient registries to enable large-scale genotype-phenotype studies.
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Registered trials
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