ArticleTrials2010
Legislation for trial registration and data transparency.
Article in Trials, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comprehensive review of Korean Medicine registries 2015-2023.Frontiers in medicine · 2024Pooled it
- Characteristics of pediatric interventional drug trials registered between 2015 and 2024 on ClinicalTrials.gov.Frontiers in pediatrics · 2025Article
- Evolution of Clinical Trials of Systemic Therapies for Hepatocellular Carcinoma Between 2005 and 2024: Based on ClinicalTrials.gov.Gastro hep advances · 2025Review
- Studies with statistically significant effect estimates are more frequently published compared to non-significant estimates in oral health journals.BMC medical research methodology · 2023Article
- The characteristics of registered acupuncture clinical trials enrolling cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Review
- Quality assessment of clinical trial registration with traditional Chinese medicine in WHO registries.BMJ open · 2019Article
- Kidney function and specific mortality in 60-80 years old post-myocardial infarction patients: A 10-year follow-up study.PloS one · 2017Article
- Article
- Fraud in scientific research - birth of the Concordat to uphold research integrity in the United Kingdom.Journal of the Royal Society of Medicine · 2014Article
- Article
- Use of data from registered clinical trials to identify gaps in health research and development.Bulletin of the World Health Organization · 2013Article
- Article
- Timely and complete publication of economic evaluations alongside randomized controlled trials.PharmacoEconomics · 2013Article
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- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Public confidence in clinical trials has been eroded by data suppression, misrepresentation and manipulation. Although various attempts have been made to achieve universal trial registration- e.g., Declaration of Helsinki, WHO clinical Trial Registry Platform (WHO ICTRP), the International Committee of Medical Journal Editors requirement- they have not succeeded, probably because they lack the enough power of enforcement.Legislation appears to be the most efficient and effective means to ensure that all researchers register their trials and disseminate their data accurately and in a timely manner. We propose that a global network be established. This could be accomplished in two steps. The first step is to legislate about trial registration and data transparency, such as USA's FDAAA Act 2007; and the second step to establish a global network to ensure uniform, international consistency in policy and enforcement of trial registration and data transparency.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.