ArticleThe journal of physical chemistry. B2010
Orientation determination of interfacial beta-sheet structures in situ.
Article in The journal of physical chemistry. B, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- The Dysferlin C2A Domain Binds PI(4,5)P2 and Penetrates Membranes.Journal of molecular biology · 2023Article
- True Origin of Amide I Shifts Observed in Protein Spectra Obtained with Sum Frequency Generation Spectroscopy.The journal of physical chemistry letters · 2023Article
- Polarization-Dependent Heterodyne-Detected Sum-Frequency Generation Spectroscopy as a Tool to Explore Surface Molecular Orientation and Ångström-Scale Depth Profiling.The journal of physical chemistry. B · 2022Review
- Acidic pH Promotes Refolding and Macroscopic Assembly of Amyloid β (16-22) Peptides at the Air-Water Interface.The journal of physical chemistry letters · 2022Article
- Intrinsically Disordered Osteopontin Fragment Orders During Interfacial Calcium Oxalate Mineralization.Angewandte Chemie (International ed. in English) · 2021Article
- Ice-nucleating proteins are activated by low temperatures to control the structure of interfacial water.Nature communications · 2021Article
- Role of Water in CaCOJournal of the American Chemical Society · 2021Article
- Otoferlin C2F Domain-Induced Changes in Membrane Structure Observed by Sum Frequency Generation.Biophysical journal · 2019Article
- Peptide-Controlled Assembly of Macroscopic Calcium Oxalate Nanosheets.The journal of physical chemistry letters · 2019Article
- Structure of von Willebrand factor A1 on polystyrene determined from experimental and calculated sum frequency generation spectra.Biointerphases · 2018Article
- Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions.Angewandte Chemie (International ed. in English) · 2018Review
- Nonlinear Optical Methods for Characterization of Molecular Structure and Surface Chemistry.Topics in catalysis · 2018Article
- Observation of pH-Induced Protein Reorientation at the Water Surface.The journal of physical chemistry letters · 2017Article
- Predicting the orientation of protein G B1 on hydrophobic surfaces using Monte Carlo simulations.Biointerphases · 2016Article
- In Situ Investigation of Peptide-Lipid Interaction Between PAP248-286 and Model Cell Membranes.The Journal of membrane biology · 2016Article
- Evidence of a molecular boundary lubricant at snakeskin surfaces.Journal of the Royal Society, Interface · 2015Article
- Broad-Bandwidth Chiral Sum Frequency Generation Spectroscopy for Probing the Kinetics of Proteins at Interfaces.Langmuir : the ACS journal of surfaces and colloids · 2015Article
- Probing Site-Specific Structural Information of Peptides at Model Membrane Interface In Situ.Journal of the American Chemical Society · 2015Article
- Theoretical Sum Frequency Generation Spectroscopy of Peptides.The journal of physical chemistry. B · 2015Article
- Characterization of Parallel β-Sheets at Interfaces by Chiral Sum Frequency Generation Spectroscopy.The journal of physical chemistry letters · 2015Article
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3 authors.
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Abstract
Structural information such as orientations of interfacial proteins and peptides is important for understanding properties and functions of such biological molecules, which play crucial roles in biological applications and processes such as antimicrobial selectivity, membrane protein activity, biocompatibility, and biosensing performance. The alpha-helical and beta-sheet structures are the most widely encountered secondary structures in peptides and proteins. In this paper, for the first time, a method to quantify the orientation of the interfacial beta-sheet structure using a combined attenuated total reflectance Fourier transformation infrared spectroscopic (ATR-FTIR) and sum frequency generation (SFG) vibrational spectroscopic study was developed. As an illustration of the methodology, the orientation of tachyplesin I, a 17 amino acid peptide with an antiparallel beta-sheet, adsorbed to polymer surfaces as well as associated with a lipid bilayer was determined using the regular and chiral SFG spectra, together with polarized ATR-FTIR amide I signals. Both the tilt angle (theta) and the twist angle (psi) of the beta-sheet at interfaces are determined. The developed method in this paper can be used to obtain in situ structural information of beta-sheet components in complex molecules. The combination of this method and the existing methodology that is currently used to investigate alpha-helical structures will greatly broaden the application of optical spectroscopy in physical chemistry, biochemistry, biophysics, and structural biology.
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