ArticleInfection and immunity1991
Characterization of cell wall proteins of yeast and hydrophobic mycelial cells of Candida albicans.
Article in Infection and immunity, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 80 citations in OpenAlex.
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- Assessment of Antifungal Activity of Bakuchiol on Oral-Associated Candida spp.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- An analysis of the impact of NRG1 overexpression on the Candida albicans response to specific environmental stimuli.Mycopathologia · 2010Article
- A Candida albicans early stage biofilm detachment event in rich medium.BMC microbiology · 2009Article
- Beta-1,2 oligomannose adhesin epitopes are widely distributed over the different families of Candida albicans cell wall mannoproteins and are associated through both N- and O-glycosylation processes.Infection and immunity · 2008Article
- Lipase 8 affects the pathogenesis of Candida albicans.Infection and immunity · 2007Article
- Systematic survey of nonspecific agglutination by Candida spp. in latex assays.Journal of clinical microbiology · 2007Article
- Preparation of combined extract of cell wall and cytosol antigens of Candida albicans for immunoblot analysis.Journal of clinical laboratory analysis · 2007Article
- Cloning and analysis of a Candida albicans gene that affects cell surface hydrophobicity.Journal of bacteriology · 2001Article
- Coaggregation of Candida dubliniensis with Fusobacterium nucleatum.Journal of clinical microbiology · 1999Article
- Detection of antibodies to Candida albicans germ tubes during experimental infections by different Candida species.Clinical and diagnostic laboratory immunology · 1998Article
- Cell wall and secreted proteins of Candida albicans: identification, function, and expression.Microbiology and molecular biology reviews : MMBR · 1998Review
- Serologic response to cell wall mannoproteins and proteins of Candida albicans.Clinical microbiology reviews · 1998Review
- The Candida albicans HYR1 gene, which is activated in response to hyphal development, belongs to a gene family encoding yeast cell wall proteins.Journal of bacteriology · 1996Article
- Evidence for presence in the cell wall of Candida albicans of a protein related to the hsp70 family.Infection and immunity · 1996Article
- Binding of human fibronectin to Aspergillus fumigatus conidia.Infection and immunity · 1996Article
- Common and form-specific cell wall antigens of Candida albicans as released by chemical and enzymatic treatments.Mycopathologia · 1996Article
- Complex interaction between different proteinaceous components within the cell-wall structure of Candida albicans.Mycopathologia · 1995Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell surface hydrophobicity (CSH) of blastoconidia and blastoconidia bearing germ tubes of Candida albicans ATCC 26555 was monitored by assessing attachment of polystyrene microspheres to the cell surface, and we found that mature hyphae were significantly hydrophobic. Treatment of intact cells with low concentrations of beta-glucanase (Zymolyase 20T) or proteases abolished or significantly reduced attachment of latex beads to hyphae. This effect paralleled an obvious reduction in CSH of the entire cell population, as measured by an aqueous-hydrocarbon biphasic partitioning assay. Analysis of the cell wall material released by Zymolyase and adsorbed on polystyrene microspheres indicated that germ tube-specific cell wall proteins and mannoproteins with apparent molecular masses of 20 to 67 kDa may be responsible for the hydrophobicity of hyphae. Zymolyase released from blastoconidia cell walls a different set of proteins and mannoproteins that were able to adsorb to polystyrene microbeads. Such molecular species might in turn be responsible for the CSH exhibited by blastoconidium populations as determined by the biphasic partitioning assay, although these probably hydrophobic components can be masked on the surface of blastoconidia, as the latter had no or very few latex microspheres attached to their surfaces. Treatment of cells of both C. albicans morphologies with 2-mercaptoethanol released qualitatively distinct species of polystyrene-adsorbed proteins and mannoproteins from yeast and mycelial cells. These observations suggested that hydrophobic proteins and mannoproteins that could be associated with CSH are bound to the cell wall structure through diverse types of linkages.
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