ArticlePloS one2010
An integrative model for phytochrome B mediated photomorphogenesis: from protein dynamics to physiology.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 60 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
60 citing papers in PubMed, 112 citations in OpenAlex.
- Cytokinin downregulates Photosystem II photochemistry during prolonged darkness in a phytochrome B-dependent manner.The New phytologist · 2026Article
- Article
- Plant Morphology and a Phytochrome B Model Reveal That the Effects of Far-Red Light on Shade-Avoidance-Like Responses Persist Under High Light Intensity.Plant, cell & environment · 2025Article
- Nonlinear optical properties of photosensory core modules of monomeric and dimeric bacterial phytochromes.Protein science : a publication of the Protein Society · 2025Article
- What is going on inside of phytochrome B photobodies?The Plant cell · 2024Review
- Liquid-liquid phase separation in plants: Advances and perspectives from model species to crops.Plant communications · 2024Review
- The interactive effects between far-red light and temperature on lettuce growth and morphology diminish at high light intensity.Frontiers in plant science · 2024Article
- Mathematical Modeling of Photo- and Thermomorphogenesis in Plants.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Unravelling marker trait associations linking nutritional value with pigmentation in rice seed.The plant genome · 2023Article
- Phytochromes transmit photoperiod information via the evening complex in Brachypodium.Genome biology · 2023Article
- Phase separation and molecular ordering of the prion-like domain of the Arabidopsis thermosensory protein EARLY FLOWERING 3.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Moonlight Is Perceived as a Signal Promoting Genome Reorganization, Changes in Protein and Metabolite Profiles and Plant Growth.Plants (Basel, Switzerland) · 2023Article
- SUPPRESSOR OF PHYTOCHROME B-4 #3 reduces the expression of PIF-activated genes and increases expression of growth repressors to regulate hypocotyl elongation in short days.BMC plant biology · 2022Article
- Hysteresis in PHYTOCHROME-INTERACTING FACTOR 4 and EARLY-FLOWERING 3 dynamics dominates warm daytime memory in Arabidopsis.The Plant cell · 2022Article
- Review: the effect of light on the key pigment compounds of photosensitive etiolated tea plant.Botanical studies · 2021Review
- Plant multiscale networks: charting plant connectivity by multi-level analysis and imaging techniques.Science China. Life sciences · 2021Review
- Carotenoid Biosynthesis and Plastid Development in Plants: The Role of Light.International journal of molecular sciences · 2021Review
- Out of the Dark and Into the Light: A New View of Phytochrome Photobodies.Frontiers in plant science · 2021Review
- Photons from NIR LEDs can delay flowering in short-day soybean and Cannabis: Implications for phytochrome activity.PloS one · 2021Article
- A Multifaceted Action of Phytochrome B in Plant Environmental Adaptation.Frontiers in plant science · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
Abstract
backgroundPlants have evolved various sophisticated mechanisms to respond and adapt to changes of abiotic factors in their natural environment. Light is one of the most important abiotic environmental factors and it regulates plant growth and development throughout their entire life cycle. To monitor the intensity and spectral composition of the ambient light environment, plants have evolved multiple photoreceptors, including the red/far-red light-sensing phytochromes. METHODOLOGY/PRINCIPAL
findingsWe have developed an integrative mathematical model that describes how phytochrome B (phyB), an essential receptor in Arabidopsis thaliana, controls growth. Our model is based on a multiscale approach and connects the mesoscopic intracellular phyB protein dynamics to the macroscopic growth phenotype. To establish reliable and relevant parameters for the model phyB regulated growth we measured: accumulation and degradation, dark reversion kinetics and the dynamic behavior of different nuclear phyB pools using in vivo spectroscopy, western blotting and Fluorescence Recovery After Photobleaching (FRAP) technique, respectively. CONCLUSIONS/SIGNIFICANCE: The newly developed model predicts that the phyB-containing nuclear bodies (NBs) (i) serve as storage sites for phyB and (ii) control prolonged dark reversion kinetics as well as partial reversibility of phyB Pfr in extended darkness. The predictive power of this mathematical model is further validated by the fact that we are able to formalize a basic photobiological observation, namely that in light-grown seedlings hypocotyl length depends on the total amount of phyB. In addition, we demonstrate that our theoretical predictions are in excellent agreement with quantitative data concerning phyB levels and the corresponding hypocotyl lengths. Hence, we conclude that the integrative model suggested in this study captures the main features of phyB-mediated photomorphogenesis in Arabidopsis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.