ReviewNeuroscience bulletin2010
The clinical manifestations and pathophysiology of cerebral small vessel disease.
Review in Neuroscience bulletin, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- White matter hyperintensities volume and cognition: A meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- The significant effects of cerebral microbleeds on cognitive dysfunction: An updated meta-analysis.PloS one · 2017Pooled it
- Trial
- Article
- Development and internal validation of a spatiotemporal gait parameter-based diagnostic model for cerebral small vessel disease.Frontiers in aging neuroscience · 2026Article
- Therapeutic potential of mesenchymal stem cells for cerebral small vessel disease.Regenerative therapy · 2024Review
- Vascular contributions to Alzheimer's disease.Translational research : the journal of laboratory and clinical medicine · 2023Review
- Pathological changes within the cerebral vasculature in Alzheimer's disease: New perspectives.Brain pathology (Zurich, Switzerland) · 2022Review
- Association between Twenty-Four-Hour Ambulatory Blood Pressure Variability and Cerebral Small Vessel Disease Burden in Acute Ischemic Stroke.Behavioural neurology · 2022Article
- The Effect of Guilingji Capsules on Vascular Mild Cognitive Impairment: A Randomized, Double-Blind, Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Diagnostic Values of Serum Levels of Homocysteine, Heat Shock Protein 70 and High-Sensitivity C-Reactive Protein for Predicting Vascular Cognitive Impairment.Neuropsychiatric disease and treatment · 2022Article
- Total Cerebral Small Vessel Disease Burden on MRI Correlates With Cognitive Impairment in Outpatients With Amnestic Disorders.Frontiers in neurology · 2021Article
- Cerebral Small Vessel Disease.International journal of molecular sciences · 2020Review
- Article
- Association of COL4A2 Gene Polymorphisms with Lacunar Stroke in Xinjiang Han Populations.Journal of molecular neuroscience : MN · 2019Article
- Article
- Neuroimaging studies on cognitive impairment due to cerebral small vessel disease.Stroke and vascular neurology · 2019Review
- Diagnostic Values of Serum Levels of Homocysteine and Uric Acid for Predicting Vascular Mild Cognitive Impairment in Patients with Cerebral Small Vessel Disease.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Experimental animal models and inflammatory cellular changes in cerebral ischemic and hemorrhagic stroke.Neuroscience bulletin · 2015Review
- Cerebral small vessel disease and Alzheimer's disease.Clinical interventions in aging · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small vessel disease (SVD) is responsible for brain chronic circular disorder, and accounts for 20%-30% cases of ischemic stroke as well as cerebral hemorrhage, and to a great extent, encephalopathy. Binswanger's disease and multiple small strokes, which are common in older people, are also closely associated with SVD. These disorders often cause decline in cognition, vascular dementia, impairment in gait and balance, mood depression, and urinary incontinence, and often brings great social and economic burdens. SVD-related encephalopathy increases the incidences of fall, disability and death in elderly people. With the aging of the society, more attention should be paid to the importance of early diagnosis and prophylactic treatment of SVD. Here the clinical manifestations and pathophysiology of SVD are reviewed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.