ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2010
Adipose tissue and volumetric bone mineral density of older Afro-Caribbean men.
Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
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- Obesity as a Multifactorial Chronic Disease: Molecular Mechanisms, Systemic Impact, and Emerging Digital Interventions.Current issues in molecular biology · 2025Review
- Changes in Bone Microarchitecture and Inflammatory Cytokines After Cure of Chronic Hepatitis C Infection With Direct-Acting Antiviral Therapy.Open forum infectious diseases · 2025Article
- Abnormal Trabecular and Cortical Bone Microarchitecture in Chronic Hepatitis C Infection and Associations With Select Inflammatory Cytokines.Open forum infectious diseases · 2025Article
- Relationship between abdominal fat volume and bone base material pairs from dual-energy spectral computed tomography in young and middle-aged patients with metabolic syndrome.Quantitative imaging in medicine and surgery · 2024Article
- Association between segmental body composition and bone mineral density in US adults: results from the NHANES (2011-2018).BMC endocrine disorders · 2023Article
- Association of visceral and subcutaneous fat with bone mineral density in US adults: a cross-sectional study.Scientific reports · 2023Article
- Associations between fat distribution and volumetric bone mineral density in Chinese adults.Endocrine · 2014Article
- Muscle density predicts changes in bone density and strength: a prospective study in girls.Journal of musculoskeletal & neuronal interactions · 2014Article
- Effects of physical activity and muscle quality on bone development in girls.Medicine and science in sports and exercise · 2013Article
- Fat mass increase in 7-year-old children: more bone area but lower bone mineral density.Journal of bone and mineral metabolism · 2013Article
- Relation of visceral and subcutaneous adipose tissue to bone mineral density in chinese women.International journal of endocrinology · 2013Article
- Longitudinal relationships between whole body and central adiposity on weight-bearing bone geometry, density, and bone strength: a pQCT study in young girls.Archives of osteoporosis · 2013Article
- Body composition and skeletal health: too heavy? Too thin?Current osteoporosis reports · 2012Review
- Relationship between MRI-measured bone marrow adipose tissue and hip and spine bone mineral density in African-American and Caucasian participants: the CARDIA study.The Journal of clinical endocrinology and metabolism · 2012Article
- Relationship between abdominal fat and bone mineral density in white and African American adults.Bone · 2012Article
- Skeletal muscle fat content is inversely associated with bone strength in young girls.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2011Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
Although low body weight is a risk factor for osteoporosis-related fractures, conflicting data exist for the association between adiposity and bone mineral density (BMD). Studies examining these relationships have measured body fat and BMD with dual-energy X-ray absorptiometry (DXA), which cannot distinguish subcutaneous adipose tissue area (SAT) from total adiposity or trabecular from cortical bone. To investigate the relationship between adiposity and BMD further, we analyzed body composition and adipose tissue distribution by quantitative computed tomography (QCT) in 1829 Afro-Caribbean men aged 40 years and older from a population-based sample. Cortical volumetric BMD, muscle cross-sectional area, total adipose tissue area (TAT), and percentage SAT were measured at the proximal tibia. Trabecular volumetric BMD was measured at the distal tibia. We used analysis of covariance to test for associations between quartile of the adipose tissue measures and BMD, adjusting for anthropometric, health, and lifestyle factors. Higher TAT was associated with lower cortical BMD in both unadjusted and adjusted models (p < .001). Men with a higher percentage SAT had greater cortical BMD (p < .001). Similar associations were seen between percent SAT and trabecular BMD at the distal tibia. These results indicate that total adiposity is a potentially important correlate of bone mass in older men and that different fat depots may have opposing associations with bone mass. Additional research is needed to better understand the mechanisms underlying the relationship between body fat distribution and bone mass.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.